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Database: UniProt
Entry: A0A072V8S7_MEDTR
LinkDB: A0A072V8S7_MEDTR
Original site: A0A072V8S7_MEDTR 
ID   A0A072V8S7_MEDTR        Unreviewed;       513 AA.
AC   A0A072V8S7;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   23-MAY-2018, entry version 13.
DE   SubName: Full=M28 Zn-peptidase nicastrin {ECO:0000313|EMBL:KEH34600.1};
GN   Name=11411239 {ECO:0000313|EnsemblPlants:KEH34600};
GN   OrderedLocusNames=MTR_3g065110 {ECO:0000313|EMBL:KEH34600.1};
OS   Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae;
OC   Trifolieae; Medicago.
OX   NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH34600.1, ECO:0000313|Proteomes:UP000002051};
RN   [1] {ECO:0000313|EMBL:KEH34600.1, ECO:0000313|EnsemblPlants:KEH34600, ECO:0000313|Proteomes:UP000002051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A17 {ECO:0000313|EMBL:KEH34600.1}, and cv. Jemalong A17
RC   {ECO:0000313|EnsemblPlants:KEH34600,
RC   ECO:0000313|Proteomes:UP000002051};
RX   PubMed=22089132; DOI=10.1038/nature10625;
RA   Young N.D., Debelle F., Oldroyd G.E.D., Geurts R., Cannon S.B.,
RA   Udvardi M.K., Benedito V.A., Mayer K.F.X., Gouzy J., Schoof H.,
RA   Van de Peer Y., Proost S., Cook D.R., Meyers B.C., Spannagl M.,
RA   Cheung F., De Mita S., Krishnakumar V., Gundlach H., Zhou S.,
RA   Mudge J., Bharti A.K., Murray J.D., Naoumkina M.A., Rosen B.,
RA   Silverstein K.A.T., Tang H., Rombauts S., Zhao P.X., Zhou P.,
RA   Barbe V., Bardou P., Bechner M., Bellec A., Berger A., Berges H.,
RA   Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA   Deshpande S., Dai X., Doyle J.J., Dudez A.-M., Farmer A.D.,
RA   Fouteau S., Franken C., Gibelin C., Gish J., Goldstein S.,
RA   Gonzalez A.J., Green P.J., Hallab A., Hartog M., Hua A.,
RA   Humphray S.J., Jeong D.-H., Jing Y., Jocker A., Kenton S.M.,
RA   Kim D.-J., Klee K., Lai H., Lang C., Lin S., Macmil S.L.,
RA   Magdelenat G., Matthews L., McCorrison J., Monaghan E.L., Mun J.-H.,
RA   Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA   Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C.,
RA   Sallet E., Samain S., Samson N., Sanders I., Saurat O., Scarpelli C.,
RA   Schiex T., Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S.,
RA   Singer S.R., Sinharoy S., Sterck L., Viollet A., Wang B.-B., Wang K.,
RA   Wang M., Wang X., Warfsmann J., Weissenbach J., White D.D.,
RA   White J.D., Wiley G.B., Wincker P., Xing Y., Yang L., Yao Z., Ying F.,
RA   Zhai J., Zhou L., Zuber A., Denarie J., Dixon R.A., May G.D.,
RA   Schwartz D.C., Rogers J., Quetier F., Town C.D., Roe B.A.;
RT   "The Medicago genome provides insight into the evolution of rhizobial
RT   symbioses.";
RL   Nature 480:520-524(2011).
RN   [2] {ECO:0000313|EMBL:KEH34600.1, ECO:0000313|EnsemblPlants:KEH34600, ECO:0000313|Proteomes:UP000002051}
RP   GENOME REANNOTATION.
RC   STRAIN=A17 {ECO:0000313|EMBL:KEH34600.1}, and cv. Jemalong A17
RC   {ECO:0000313|EnsemblPlants:KEH34600,
RC   ECO:0000313|Proteomes:UP000002051};
RX   PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA   Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA   Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA   Schwartz D.C., Town C.D.;
RT   "An improved genome release (version Mt4.0) for the model legume
RT   Medicago truncatula.";
RL   BMC Genomics 15:312-312(2014).
RN   [3] {ECO:0000313|EnsemblPlants:KEH34600}
RP   IDENTIFICATION.
RC   STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH34600};
RG   EnsemblPlants;
RL   Submitted (APR-2015) to UniProtKB.
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DR   EMBL; CM001219; KEH34600.1; -; Genomic_DNA.
DR   RefSeq; XP_013460566.1; XM_013605112.1.
DR   EnsemblPlants; KEH34600; KEH34600; MTR_3g065110.
DR   GeneID; 11411239; -.
DR   Gramene; KEH34600; KEH34600; MTR_3g065110.
DR   Proteomes; UP000002051; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016485; P:protein processing; IEA:InterPro.
DR   InterPro; IPR008710; Nicastrin.
DR   PANTHER; PTHR21092; PTHR21092; 1.
DR   Pfam; PF05450; Nicastrin; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002051};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    483    506       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   513 AA;  55033 MW;  02026C3F7F680C64 CRC64;
     MWKSYGFPVF LLTESGTKTL QEFVLKGEDK KKAYTSNVAE FDLVMQTMKS GTHDSESCLN
     EGTCLPLGGY SVWSALPPIN NSSSKPSKPI ILTVASMDSA SFFRDRSLGA DSPISGLIAL
     LAAADALSHL DGIGDLSKQL VFVVFTGEAW GYLGSRRFLV ELDEHSDAVQ GLNHSLIEKV
     LEIGSVGKGL SQGAKNFFAH AERDSSATNQ IMVALKHAQE SLLSEDIRIT SASASNPGIP
     PSSLMTFWNK NPGISGVVLE DFDSSFVNEF YHSYLDDLSN VNSSAVVAAA SLVARTLYIL
     ASETNDVQNS TLAAINVNVS LVEQLVGCLL GCDPGLSCEL VKKYISPAST CASNYVGVIL
     DEPSSTPNPG YINDVPRFIW NFLADITSIS KENSSSGCQQ GCSGSDEVCI KAETDGKGVC
     VLSTTRYVPA YSTRLSFESG VWSVLPPNSS DKMGVVDPVW TESNWNTVGI RIYTVQIAAY
     DRVVLFGGMT LTLLAYLGIA VTRTFVAKAT KRD
//
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