ID A0A072VWV8_MEDTR Unreviewed; 1155 AA.
AC A0A072VWV8;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Myosin motor domain protein and Dil domain protein {ECO:0000313|EMBL:KEH42580.1};
GN OrderedLocusNames=MTR_1g070280 {ECO:0000313|EMBL:KEH42580.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:KEH42580.1, ECO:0000313|Proteomes:UP000002051};
RN [1] {ECO:0000313|EMBL:KEH42580.1, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:KEH42580.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH42580,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [2] {ECO:0000313|EMBL:KEH42580.1, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=A17 {ECO:0000313|EMBL:KEH42580.1}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:KEH42580,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [3] {ECO:0000313|EnsemblPlants:KEH42580}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:KEH42580};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. Plant myosin class XI subfamily.
CC {ECO:0000256|ARBA:ARBA00008049}.
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DR EMBL; CM001217; KEH42580.1; -; Genomic_DNA.
DR RefSeq; XP_013468543.1; XM_013613089.1.
DR AlphaFoldDB; A0A072VWV8; -.
DR STRING; 3880.A0A072VWV8; -.
DR EnsemblPlants; KEH42580; KEH42580; MTR_1g070280.
DR Gramene; KEH42580; KEH42580; MTR_1g070280.
DR Proteomes; UP000002051; Chromosome 1.
DR ExpressionAtlas; A0A072VWV8; differential.
DR GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0030050; P:vesicle transport along actin filament; IBA:GO_Central.
DR CDD; cd01384; MYSc_Myo11; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036018; MYSc_Myo11.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF772; MYOSIN-5; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000002051}.
FT DOMAIN 8..57
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 62..733
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 614..636
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 887..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 960..1015
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 887..903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 156..163
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1155 AA; 130915 MW; 287B66EA7F7A61AF CRC64;
MGMPENIIVG SHVWVADPEL VWIDGVVLNI NGEDAEIQTS NEKKVVSRLS KLHPKDTDAP
TDGFDDMTKL AYLHEPGVLY NLESRYKINE IYTYSGNILI AINPFQSLPH LYDANAMKRY
KGERIGNLSP HVFAIAEAAY RAMITEEKSN SILVSGESGA GKTETTKMLM LYLAYLGGHT
ASEGRTVEQQ VLESNPVLEA FGNAKTVRND NSSRFGKFVE IQFDKYGRIS GAAIRTYLLE
KSRVCQISDP ERNYHCFYLL CASPPEEKEK YKLGDPRSFH YLNQSSCYEL AGVNAAQEYL
STKRAMDIVG ISQEEQDAIF RVIAAILHLG NIKFEKSEEE TDSSVLADKD SKFHLETTAE
LLMCDSNAVE VALCKRVMIT PEEIIERSLD PVAATVSRDG LAKTLYSRLF DWLVQKINLS
IGQDSNSKCL IGVLDIYGFE SFQTNSFEQF CINFTNEKLQ QHFNQHVFKM EQEEYTKEAI
DWSYLEFVDN QDVLDLIEKK PGGIIALLDE ACMFPKSTHE TFSTKLYQTF KDHKRFIKPK
LARSDFTVVH YAGVVQYQSE HFIDKNKDYV VPEHQVMLST SKCSFVSGLF PPLSEETAKS
AKFSSIGSRF KLQLQHLMEA LNLTEPHYIR CVKPNTLLKP GIFENMNVMH QLRSGGVLEA
VRIKCAGFPT HRTFHEFLTR VGILAPEILR GNFEEKESCK MILEKIGLTG YQIGQTKLFL
RAGHMAELDA RRAYMLSNSA TIIQKHTRTH FSQKRYTTLR KSSLFLQSIC RGELARRQYY
HMKRKAAAIK IQAYTRGRIA RKCYSEMKTS VVVLQSGFQA MAARRARDKF RHIRQTRSST
IIQSYWRRHK ALVDYQNLKK ASIISQSVNH SNDEQEQKVM EISVENESTA MEESSNSLRE
ESSSSFQDNE RIEAIKDFSS PIIDAERNEA IRDCSSPHRD TESNENIRDF SSPLGDTEKI
EALSAEIKTL KFMLQEEKQK TDEYERKYVE AQGSSEELRK KLTETEKRVY QLQDSLNRMI
SSMSSQVAEL KTILSTSSRL SSTFRPIARV DVASSNSDSS STDSDFTFPA PVANSEALSS
TQLVVQDVTA AEGSAFNLGF TMYITDKDLE VKKKVRLMIS SSKTCVSSIW LKFSSPPASG
ETTKKVREKD EGCIG
//
