ID A0A073AWA5_9PSEU Unreviewed; 503 AA.
AC A0A073AWA5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:KEI44073.1};
GN ORFNames=GU90_11345 {ECO:0000313|EMBL:KEI44073.1};
OS Saccharopolyspora rectivirgula.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=28042 {ECO:0000313|EMBL:KEI44073.1, ECO:0000313|Proteomes:UP000031419};
RN [1] {ECO:0000313|EMBL:KEI44073.1, ECO:0000313|Proteomes:UP000031419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43113 {ECO:0000313|EMBL:KEI44073.1,
RC ECO:0000313|Proteomes:UP000031419};
RA Barrera C., Millon L., Rognon B., Zaugg C., Monod M.;
RT "Saccharopolyspora rectivirgula DSM-43113 Genome sequencing.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEI44073.1}.
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DR EMBL; JNVU01000029; KEI44073.1; -; Genomic_DNA.
DR RefSeq; WP_051707759.1; NZ_JNVU01000029.1.
DR AlphaFoldDB; A0A073AWA5; -.
DR STRING; 28042.GU90_11345; -.
DR eggNOG; COG0427; Bacteria.
DR OrthoDB; 9801795at2; -.
DR Proteomes; UP000031419; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KEI44073.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031419}.
FT DOMAIN 9..219
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 331..468
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 293
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 363
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 383
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 387
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 407
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 503 AA; 55013 MW; C71C31ABAC605CCA CRC64;
MTGRIRNQRL AARVVDAERA AELIESGDNV GMSGFTGAGY PKEVPGALAK RVSVAATEGK
PMKVGLWTGA STAPELDGAL AEVDGVDLRL PYQSDPTSRA KINSGEMHYT DIHLSHVAQQ
VWEGFLGPLD VAVVEVAGIT EDGRLIPSSS VGNNKTWLEQ ADRIILEVNS WQSADLEGMH
DIYYGTALPP NRKPIPLTRP ADRIGTPYLE CPVDKVIAVV ETHSPDRNTV FKEPDENSRR
IAEHVLDFFD AEVRNGRLPR NLLPLQSGVG NIANAVLAGL DKGPFTDLTA YTEVIQDGML
HLIDTGTLRT ASATALSLSP DAVERFNNNA ADYRDRIVLR PQEISNHPEV VRRLGCLAMN
GIIEADIYGN VNSTHMMGSR IQNGIGGSGD FARNAYISIF MTPSTAKNGA ISTIVPMVSH
VDHTEHDVDI IVTEQGLADL RGLSPRRRAE VLIENCAHPD FRPLLRDYYE RALRDAYGRH
TPHLLSEALS WHQRYVDTGS MLP
//
