ID A0A073AXF9_9PSEU Unreviewed; 790 AA.
AC A0A073AXF9;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KEI43742.1};
GN ORFNames=GU90_14090 {ECO:0000313|EMBL:KEI43742.1};
OS Saccharopolyspora rectivirgula.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=28042 {ECO:0000313|EMBL:KEI43742.1, ECO:0000313|Proteomes:UP000031419};
RN [1] {ECO:0000313|EMBL:KEI43742.1, ECO:0000313|Proteomes:UP000031419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43113 {ECO:0000313|EMBL:KEI43742.1,
RC ECO:0000313|Proteomes:UP000031419};
RA Barrera C., Millon L., Rognon B., Zaugg C., Monod M.;
RT "Saccharopolyspora rectivirgula DSM-43113 Genome sequencing.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Antibiotic biosynthesis. {ECO:0000256|ARBA:ARBA00004792}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEI43742.1}.
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DR EMBL; JNVU01000035; KEI43742.1; -; Genomic_DNA.
DR RefSeq; WP_037343158.1; NZ_JNVU01000035.1.
DR AlphaFoldDB; A0A073AXF9; -.
DR STRING; 28042.GU90_14090; -.
DR eggNOG; COG0183; Bacteria.
DR eggNOG; COG1024; Bacteria.
DR OrthoDB; 4284283at2; -.
DR Proteomes; UP000031419; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 2.40.50.840; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR040771; TLP1_add_C.
DR PANTHER; PTHR11941:SF54; ENOYL-COA HYDRATASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11941; ENOYL-COA HYDRATASE-RELATED; 1.
DR Pfam; PF00378; ECH_1; 1.
DR Pfam; PF18313; TLP1_add_C; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Reference proteome {ECO:0000313|Proteomes:UP000031419};
KW Transferase {ECO:0000313|EMBL:KEI43742.1}.
FT DOMAIN 427..506
FT /note="Thiolase-like protein type 1 additional C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18313"
SQ SEQUENCE 790 AA; 84657 MW; DEA4EB8DF202ECE0 CRC64;
MSNHDIDPRT PVLVGVGQFA ERLDDPDYRR LSAVDIAAEA ARAALADTGT APEVAAKAID
TVAGIRQFEI STPGATAPLG RSNNYPRSVA KRIGAAPRRA ILEVTGGQGP QHLVTELAGT
IAEGGAEVAL AFGSEAISTV EHFARAEDKP DFTEHVDGDL EDRGWALKGL LSQRQMMHGL
ADPPSQYALF DNARRARLGM SREDYATAMG ELFAPFTEVA AKNPYAAAPV ERSAQELVTP
TEKNRLISDP YTRYIVARDK VNQGAAVLLM SVAAADRLGV PPEKRVFLHG HADLRERDLM
ERQDLSRSPA AVMAARHALE VAGIDVADLS TLDLYSCFPA PVFNICDGLG LSPDDPRGLT
VTGGLPFFGG AGNNYSMHAI AETVQRMRAN PGTFGFVGAN GGAMSKYSVG IYSTTPTEWR
PDNSAALQAE IDSWPAPEEA IRADGWATIE TCTVKHGRDG TRTGIVIGRL EADDRRFIAR
TQDGDEEMLD LLSTGEPIGA RVHVRSFGFG NRVTTTEERM NALFPPKPAV LHDDHEFVRV
HRDGHLLEIT IDRPESRNSL HPPAHEELDE IFNAYFADPE LRVAIITGAG DEAFCAGNDL
RYSASGKPVW TPKSGFGGLT SRRDMTKPVI AAVNGFAVGG GFEIALACHL VVADETAQFA
LPEVKVGLVA AAGGLVRLPR ALPQKLATEM ILTGRRLSAA EAASRGLVNR VTEAGGALDG
ARALAAEILE GSPTSVRVSL QIMNETQGIA DTVDAVEHPS DALDELVLSQ DMVEGVTAFV
EKREPVWRNR
//
