ID A0A073B1I9_9PSEU Unreviewed; 299 AA.
AC A0A073B1I9;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=TetR family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=GU90_01390 {ECO:0000313|EMBL:KEI45883.1};
OS Saccharopolyspora rectivirgula.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=28042 {ECO:0000313|EMBL:KEI45883.1, ECO:0000313|Proteomes:UP000031419};
RN [1] {ECO:0000313|EMBL:KEI45883.1, ECO:0000313|Proteomes:UP000031419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43113 {ECO:0000313|EMBL:KEI45883.1,
RC ECO:0000313|Proteomes:UP000031419};
RA Barrera C., Millon L., Rognon B., Zaugg C., Monod M.;
RT "Saccharopolyspora rectivirgula DSM-43113 Genome sequencing.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEI45883.1}.
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DR EMBL; JNVU01000005; KEI45883.1; -; Genomic_DNA.
DR RefSeq; WP_029720997.1; NZ_JNVU01000005.1.
DR AlphaFoldDB; A0A073B1I9; -.
DR STRING; 28042.GU90_01390; -.
DR eggNOG; COG1309; Bacteria.
DR OrthoDB; 1669699at2; -.
DR Proteomes; UP000031419; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF253; HTH-TYPE TRANSCRIPTIONAL REPRESSOR KSTR2; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000031419};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 107..167
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 130..149
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 77..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 32763 MW; 51865EC2658D050D CRC64;
MTASSATGPP GAQIRAARLR RNLTVRTLAS AVGVSPATIS QIENGRTKVS VSRLGRIADA
LDMTVAEILD IDPRGETAHR GRAAKPSGAA AATPHVPPIP HWRDYEPLDF DPVLAAALSE
FVEIGYHGAT VRSIAARCGF SVSGIYHYYT SKQQMLVTIL ERTMTELLAR AEAARGEGND
PVERFSFLIE HLALFHTHRR ELGFVGASEM RSLAGSARRR IAAMRVAQQR MVDAEAEQAA
RQGDFCTSHP REAARAVVTM CTALSGWWRP DGPLAPEQIA EQYVDFALDL MRHRKTRQR
//
