ID A0A073CKT2_PLAAG Unreviewed; 897 AA.
AC A0A073CKT2;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cysteine protease {ECO:0000313|EMBL:KEI68884.1};
DE EC=3.4.22.- {ECO:0000313|EMBL:KEI68884.1};
GN ORFNames=A19Y_4193 {ECO:0000313|EMBL:KEI68884.1};
OS Planktothrix agardhii NIVA-CYA 126/8.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Planktothrix.
OX NCBI_TaxID=388467 {ECO:0000313|EMBL:KEI68884.1, ECO:0000313|Proteomes:UP000027395};
RN [1] {ECO:0000313|EMBL:KEI68884.1, ECO:0000313|Proteomes:UP000027395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIVA-CYA 126/8 {ECO:0000313|EMBL:KEI68884.1,
RC ECO:0000313|Proteomes:UP000027395};
RX PubMed=24907328; DOI=10.1128/AEM.01188-14;
RA Christiansen G., Goesmann A., Kurmayer R.;
RT "Elucidation of insertion elements encoded on plasmids and in vitro
RT construction of shuttle vectors from the toxic cyanobacterium
RT Planktothrix.";
RL Appl. Environ. Microbiol. 80:4887-4897(2014).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM002803; KEI68884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A073CKT2; -.
DR STRING; 388467.A19Y_4193; -.
DR PATRIC; fig|388467.6.peg.4131; -.
DR eggNOG; COG4870; Bacteria.
DR HOGENOM; CLU_322591_0_0_3; -.
DR Proteomes; UP000027395; Chromosome.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02619; Peptidase_C1; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR002477; Peptidoglycan-bd-like.
DR InterPro; IPR036365; PGBD-like_sf.
DR InterPro; IPR036366; PGBDSf.
DR PANTHER; PTHR12411:SF741; CATHEPSIN K; 1.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR Pfam; PF01471; PG_binding_1; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF47090; PGBD-like; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KEI68884.1};
KW Protease {ECO:0000313|EMBL:KEI68884.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027395}.
FT DOMAIN 627..848
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 897 AA; 104480 MW; 5D1234785D40EE2E CRC64;
MMPLNINQLG WLPDYPDSRD MTLNELSENI IKEEESKSQD CTQLQIVRLI EDLIPIPNDH
ENKKKLESLK QIIRKDQNQI SFLQCQSETK VFLYRRTTNY LVKDIQKKLD LIFENCHQYL
DLNLEYLEKL SLENGYFGEA THNLMIYFKK IWELPSQSSI VDFDYNFDSE LKGIKYYQYS
LNTTIYGILD AIYQRIYQEE PNQSLIKFGD FGDKVVVIKE KLEQLNYFPF SEQDNYKESK
YFFGYKTDLV IEFFQGFNGL QSDGIVGKVT REQLEKQLEE IPKRGIMYLQ KRLSRDFEVP
EIKFTGELDS TTKKEINKII NPSDDSDDSD ITMESVKKFL IAIIKKAENS KKYCLSQTVV
FSDLAQNYNK NDKNFTLLMV EQPISKNIIE IFKKELNLIK SGIEKNDYMI IIPMIYPLIQ
LIIRNLSDIG IHGQLDHEKM IVQAINLINI ILASDQNLPL CNPYNSIENY LQDQQLLNNT
DQRAQFLFEF IKGKKSGESE VDLKLIYYFL SQAEKKRLTF LVFITLDQIE SIISEIEETK
KPNFKQLITK INNSKKNILY QLKNMVENSE EEESNSDFFM ENICKNKTIL QICDERPKKT
LQIPLVPELE THIKTYQDLK IPVYLCLPEF VDLSHWCSPI RNQKPLNSCT AFAAIALIEY
FQNKNCDEYT NASVLFLYKV ARKLMHRQGD VGASIRETMK AMVLFGIPPE EYWPYEPSKI
DEEPSGFCYS YAENYKTIQY FRLDTPGLPA SDLLAQIKMT LVAGIPSMFG LTIYSSIYEE
FNYKRGYIPV PNKKDQVEGG HAVVAVGYDD HKIIQNSVGA LLIRNSWGTN WGERGYGWLP
YDYILRGLTS DWWSLLKAKW FETKNFGLGA NDWKYDFGVD DGKPSSKDPL PVKPSNK
//
