ID A0A073IRC8_9BACT Unreviewed; 799 AA.
AC A0A073IRC8;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Pyruvate formate-lyase {ECO:0000313|EMBL:KEJ92913.1};
GN ORFNames=EH55_00470 {ECO:0000313|EMBL:KEJ92913.1};
OS Synergistes jonesii.
OC Bacteria; Synergistota; Synergistia; Synergistales; Synergistaceae;
OC Synergistes.
OX NCBI_TaxID=2754 {ECO:0000313|EMBL:KEJ92913.1, ECO:0000313|Proteomes:UP000027665};
RN [1] {ECO:0000313|EMBL:KEJ92913.1, ECO:0000313|Proteomes:UP000027665}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=78-1 {ECO:0000313|EMBL:KEJ92913.1,
RC ECO:0000313|Proteomes:UP000027665};
RA Coil D.A., Eisen J.A., Holland-Moritz H.E.;
RT "Draft Genome Sequence of Synergistes jonesii.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEJ92913.1}.
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DR EMBL; JMKI01000012; KEJ92913.1; -; Genomic_DNA.
DR RefSeq; WP_037974922.1; NZ_JQEL01000013.1.
DR AlphaFoldDB; A0A073IRC8; -.
DR STRING; 2754.EH55_00470; -.
DR PATRIC; fig|2754.20.peg.2145; -.
DR eggNOG; COG1882; Bacteria.
DR OrthoDB; 108at2; -.
DR Proteomes; UP000027665; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.20.70.20; -; 1.
DR InterPro; IPR001150; Gly_radical.
DR InterPro; IPR004184; PFL_dom.
DR PANTHER; PTHR43641:SF2; DEHYDRATASE YBIW-RELATED; 1.
DR PANTHER; PTHR43641; FORMATE ACETYLTRANSFERASE 3-RELATED; 1.
DR Pfam; PF01228; Gly_radical; 1.
DR Pfam; PF02901; PFL-like; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR PROSITE; PS51149; GLY_RADICAL_2; 1.
DR PROSITE; PS51554; PFL; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:KEJ92913.1};
KW Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW ProRule:PRU00493}; Pyruvate {ECO:0000313|EMBL:KEJ92913.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027665}.
FT DOMAIN 10..665
FT /note="PFL"
FT /evidence="ECO:0000259|PROSITE:PS51554"
FT DOMAIN 672..793
FT /note="Glycine radical"
FT /evidence="ECO:0000259|PROSITE:PS51149"
FT MOD_RES 768
FT /note="Glycine radical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ SEQUENCE 799 AA; 89640 MW; 1DE7576873B1E5FA CRC64;
MTATEPKYMA RVNRLKKKVF ETYPEIDLED AVILTKSFLE TQGEALVTRK AKAFRRQCSE
KSVKIWDDEL IVGNSGSKIR GGILSADVCW SVLDRELETI NTREYDKFKL LPQDKKDFEE
IIRPYWKGRS NYEEWLARIP ADVAALRDNG ALYIDKKAVR GWGEVTAGYG WFIDNGVEGL
RKRILERKAK LDATVPGDYE KEVYLDALLI TAEGMEILAE RYAAEAERLA GEEKDPKRKA
ELRQIAESCR RVPAYPPRTF REAMQSFYFY QVCIFMEQNA AAYNPGRMDQ YLYPYYKADI
EAGRITPEEA QELFDCLWVK FSEPCVFQDE KTAEYSSGYP MFQNLCAGGI DKLGRDAVNE
LSYMIIQATM DTKLYQPSLS VRYNMAKNPN SFLRKIVDLM VMGTGFPAFH NDEVGIRMLM
NKGIPYNEAW NWNPGGCVET NLAGKLRGYS ALADINLGSV IEFTLLNGRC RKTGVLAGAE
TGDPLTFETY EDFLDALKRQ LHYVIRTTVK ASHIIDDICF ERPVPALSIS FEECIENAKD
YAWGGAKYNT GNGIICIGVA DLINSVAAVK RLVYDAKICD MRRLLSALAS DFEDAPEILK
ACKEAPKYGN DDAYVDELAA ELFGYIADEI ESYRSKFGVM TPGILPVSGN TPFGKEVGAL
PSGRRAWKPL ADGVSPNGGT DTNGPTAVLK SVANIPHDRF VQGTLLNMKL DPQMAQSENG
VQQIMGMLKT LCSLGVYHIQ FNVVDQKKLI EAQKHPEEYK DLLVRVAGYT AFFVELGKDV
QNDIIARTTQ SSVNCMSCG
//
