ID   A0A073K8L1_9BACI        Unreviewed;       485 AA.
AC   A0A073K8L1;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Sodium:alanine symporter {ECO:0000313|EMBL:KEK23629.1};
GN   ORFNames=BAGA_07835 {ECO:0000313|EMBL:KEK23629.1};
OS   Bacillus gaemokensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=574375 {ECO:0000313|EMBL:KEK23629.1, ECO:0000313|Proteomes:UP000027778};
RN   [1] {ECO:0000313|EMBL:KEK23629.1, ECO:0000313|Proteomes:UP000027778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15801 {ECO:0000313|EMBL:KEK23629.1,
RC   ECO:0000313|Proteomes:UP000027778};
RA   Lai Q., Liu Y., Shao Z.;
RT   "Draft genome sequence of Bacillus gaemokensis JCM 15801 (MCCC 1A00707).";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEK23629.1}.
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DR   EMBL; JOTM01000014; KEK23629.1; -; Genomic_DNA.
DR   RefSeq; WP_033675418.1; NZ_LTAQ01000069.1.
DR   AlphaFoldDB; A0A073K8L1; -.
DR   STRING; 574375.AZF08_16665; -.
DR   eggNOG; COG1115; Bacteria.
DR   Proteomes; UP000027778; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        22..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        80..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        157..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        196..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        225..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        311..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        353..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        395..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        423..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   485 AA;  52765 MW;  ECBA3421FEA439E6 CRC64;
     MDFFENVINL IHKFITTTNE YLWGYILIAL LIIIGCYFTF RAEFVQFRHI REMIRLLGDG
     ASPSTRKAQK EKHGVSSFQA FCMSTASRVG TGNLAGVAIA ISMGGAGAVF WMWLIAMIGG
     ASAFVESTLA QIYKIKDGKA FRGGPAYYME KGLNKRWMGM IFSVLITVSF GLVFNAVQAN
     TVTSAFDGAF HIDSKIVGIS LAVLLSVVIF GGVKRIARVV EMIVPIMAII YVAVALFVVV
     TNITLIPEMV KEILAHAFGI KEVAGGSFGA AVLLGVKRGL FSNEAGMGSA PNAAATANVT
     HPVKQGFIQT LGVFTDTLLI CSCTAFIILL SDVHTGTDLN GIQLTQEALK MHIGPWAPIF
     VAVAIFLFAF SSLIGNYYYG ETNIEFLNGS KTTLMIYRIA VIGMVFLGSV ATIQVVWDLA
     DLFMGVMAIF NLVTIIFLSK YAFAALKDYM KQKEAGQDPV FYADSIPGLE NTECWDREKT
     EEKVG
//