ID   A0A073KBL7_9BACI        Unreviewed;       540 AA.
AC   A0A073KBL7;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=L-lactate permease {ECO:0000256|RuleBase:RU365092};
GN   ORFNames=BAGA_06690 {ECO:0000313|EMBL:KEK23852.1};
OS   Bacillus gaemokensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=574375 {ECO:0000313|EMBL:KEK23852.1, ECO:0000313|Proteomes:UP000027778};
RN   [1] {ECO:0000313|EMBL:KEK23852.1, ECO:0000313|Proteomes:UP000027778}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15801 {ECO:0000313|EMBL:KEK23852.1,
RC   ECO:0000313|Proteomes:UP000027778};
RA   Lai Q., Liu Y., Shao Z.;
RT   "Draft genome sequence of Bacillus gaemokensis JCM 15801 (MCCC 1A00707).";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Uptake of L-lactate across the membrane. Can also transport
CC       D-lactate and glycolate. {ECO:0000256|RuleBase:RU365092}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU365092};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU365092}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the lactate permease family.
CC       {ECO:0000256|ARBA:ARBA00010100, ECO:0000256|RuleBase:RU365092}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEK23852.1}.
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DR   EMBL; JOTM01000012; KEK23852.1; -; Genomic_DNA.
DR   RefSeq; WP_033675194.1; NZ_LTAQ01000005.1.
DR   AlphaFoldDB; A0A073KBL7; -.
DR   STRING; 574375.AZF08_20640; -.
DR   eggNOG; COG1620; Bacteria.
DR   OrthoDB; 9761056at2; -.
DR   Proteomes; UP000027778; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015129; F:lactate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003804; Lactate_perm.
DR   NCBIfam; TIGR00795; lctP; 1.
DR   PANTHER; PTHR30003:SF0; GLYCOLATE PERMEASE GLCA; 1.
DR   PANTHER; PTHR30003; L-LACTATE PERMEASE; 1.
DR   Pfam; PF02652; Lactate_perm; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU365092};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365092};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU365092};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU365092};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365092}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        41..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        70..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        120..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        154..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        195..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        252..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        361..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        400..417
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        437..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
FT   TRANSMEM        520..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365092"
SQ   SEQUENCE   540 AA;  57466 MW;  8711FF2F4E934967 CRC64;
     MSTWTQIYNP LNNIWLSALV AALPILFFVL CLTVFKIKGY LSGLYSVILA IILSIFVYKM
     PATMAVSSAA FGVAAGFYPI CTIVIAAIFL YKLTVKTEQF NVIRDSISSI TSDRRLQVLL
     IAYSFGAFLE GAAGFGVPVA ITAALLVGMG FNPLKAAGIC LVANIAGGAM GAMGIPVTVP
     AQLTQMDALI VGRQTVTLLP FISFVLPFLL VAMVDGFKGI KETWQGILVS GGSFAITQFV
     VTYFLGAELT DIFAAVVSMV TLALFLRVWQ PKSSAEATDQ QVEKHGYTMK HILYAWSPFA
     FLTAFVTIFN LKAIKGLFAL DGALGSLVWN IQIPGLHNQV IKTTPIVNAD TPFAALFKLD
     VFSSTTTAIV LAIIVSLLVY RAKEQLVKEL TIETLKELKA PIYTICSVIA LAYVTNYSGM
     SSTLGLALSS TGDAFPILSP ILGWIGVFLT GSVVSSGSLF APLQAVTAAQ LDIVPSTLVA
     LNVVGGTMAK MVSPQSVAVA CAAVGLVGKE SALFKTAMKY SLIFLAIISL LQLNSIFNIF
//