ID A0A074RWS9_9AGAM Unreviewed; 1657 AA.
AC A0A074RWS9;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Signal transducer {ECO:0000313|EMBL:KEP51571.1};
GN ORFNames=V565_059510 {ECO:0000313|EMBL:KEP51571.1};
OS Rhizoctonia solani 123E.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia.
OX NCBI_TaxID=1423351 {ECO:0000313|EMBL:KEP51571.1, ECO:0000313|Proteomes:UP000027456};
RN [1] {ECO:0000313|EMBL:KEP51571.1, ECO:0000313|Proteomes:UP000027456}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=123E {ECO:0000313|EMBL:KEP51571.1,
RC ECO:0000313|Proteomes:UP000027456};
RA Cubeta M., Pakala S., Fedorova N., Thomas E., Dean R., Jabaji S., Neate S.,
RA Toda T., Tavantzis S., Vilgalys R., Bharathan N., Pakala S., Losada L.S.,
RA Zafar N., Nierman W.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEP51571.1}.
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DR EMBL; AZST01000159; KEP51571.1; -; Genomic_DNA.
DR STRING; 1423351.A0A074RWS9; -.
DR HOGENOM; CLU_001251_1_1_1; -.
DR OrthoDB; 5100844at2759; -.
DR Proteomes; UP000027456; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 2.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 2.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 2.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000027456}.
FT DOMAIN 628..811
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 852..1043
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1078..1215
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1257..1568
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 24..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1636..1657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..143
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..223
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1657 AA; 185124 MW; ADCBC94688D9DBCA CRC64;
MQSTHPNGRP GDREGELEDM FKEILGGFGE SNLTLNDPRQ PEDDQQPRRG HRVDDSIVSL
ISSYEGGDDE QEAQFPRSQG PANAYMSQRS ATRDRSRPLP QPPGASPRPG GFTAPAPPPS
LPGSMSMPSP EPFQHPGPPP GPASAFLGSS YIQPGPPKTL LNTHVRRQLP SHPEGYGQTT
SDPVRRATRR PTTAGSDTAA SPASARPRSP RLSQPNPSSP YGIPTVQVGA PDDYQPNFLS
GPPPGAMMPS TPGAASTPNL NSPGSIYRIP SPQPSYDTYN NSAYVPSNTT HSYTPSGHPP
RTTSRTHTDL YPSPISTLSP TLGSNLGRSS SASSSMLSGA PIDRNNSKSS NWSANSSLFP
GNKYPASSGS YDTATGNDAV GYLDLPSASS PVADMSYRGD QQYLEDRLAT AKGRLELHND
EDDPDDYDYS DEDETMFVNL ALLSHLAVKL RDKVPRGTHV KGSIPYTHAF TGKDIVSTIQ
STIQRQLAIT FDLSTNDRRT ALQVARSLQN QLFFYEVEWG GQALRDGVED VYMFLDDQGG
VSDQRLEREE LPTGVITLLT SCYSPSCALG LPGKCYAYGC PRGYQASAAL GRQLSAQESK
PVEKEMTVEW MDSVDPDVVR NLPESERRRQ EVIWQVVKKE EQYVNDLDTI VEIFIKPLRE
ARPPVVHGDV NHFIDNVFGN ILDIRECNRR LLEVMRVRQR EQQPVIQQIG DVFLTAAADF
RVVYPLYIGQ LPIAEKLVKD ESEANAEFRN FLEHCSRDPR ARRLDLKYFL HRPQEHLTKY
TTILDTILHD TERENADAEY LAEAMASIKN LHSVAQLRTF QNAMCRGNSA KLEWHNLVSE
EVRDGMSKQE VKRQSVIFEL IKGEMEYVKD LELLNTLFIQ PLLNEDPPPI PRSSLDRFIS
EVFSNFADVH LHHRRMLDTL HEIQREEHPI IRSISAPVFD AALNWRDAYM IYIPHYPIAE
YLVDSQKAEN KEFKAFIERQ IRVPDARRLE LKAFIHRPVA RLPRYELLLR DIMAASPMDH
EDRESIPQIV EIISELNRST NAAIGTAKQK VEIWNYASNL VWKPGEMIDL DLHNESRQLY
HFGKLYRQPE GGLDFSRWTE VFVLVFDNYL VITKPRAKDG ITKYYVNRRP IPIDLMNLIG
FGDPAQQRPT RLFSIGTKHD GPATAPGGSG ETQDSRSIFP FGIHYSGRAG GISQFFIDSQ
SAREEWKQKL EEAIEMRKVV QDSNKVFELE TLSDETFAQP KGYVPNSSWN DESSFMGGKV
TCTVPFSTAD GRGLVAIGCA EGVWIGLRHD PKSIRRVLHL KAVTQCAMLE DFGIFLVLAD
KAFFAYHIEA LVPTAGAAQM NSAQNRTPQR LSGNKDVQFF SVGQLAGRTL VVYMKKKGME
SVFRVLEPII HKINEPTRAG GAFSRFGFGQ QRSEWFRIYR DFFLPSEAFD LVFLKAKVAI
LCTKGFEIMD LADFKSVTIP QRDDARFANV ARRCDSCRPL GMLRSSENEF LLCYDEFGIY
VNRHGDPTRN VGTTIEWEGR AERVAFHPPF VVLFDSRFIE IRHVEKGNLL QIIKGEDVRC
VWDGRGAKIN PAPTPGPEGW SDGAGTQEST IHVVMNSTEP GPGGQRGKVQ YQHISELVPT
VPLFLPGPLA SPSASTYFPR PGSPSLSSPR TSVTGWP
//
