ID   A0A074TEQ1_9RHOB        Unreviewed;       833 AA.
AC   A0A074TEQ1;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:KEP70149.1};
GN   ORFNames=DL1_18630 {ECO:0000313|EMBL:KEP70149.1};
OS   Thioclava dalianensis.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Thioclava.
OX   NCBI_TaxID=1185766 {ECO:0000313|EMBL:KEP70149.1, ECO:0000313|Proteomes:UP000027725};
RN   [1] {ECO:0000313|EMBL:KEP70149.1, ECO:0000313|Proteomes:UP000027725}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DLFJ1-1 {ECO:0000313|EMBL:KEP70149.1,
RC   ECO:0000313|Proteomes:UP000027725};
RA   Lai Q., Shao Z.;
RT   "The draft genome sequence of Thioclava dalianensis DLFJ1-1.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KEP70149.1}.
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DR   EMBL; JHEH01000007; KEP70149.1; -; Genomic_DNA.
DR   RefSeq; WP_038064558.1; NZ_JHEH01000007.1.
DR   AlphaFoldDB; A0A074TEQ1; -.
DR   STRING; 1185766.SAMN05216224_101386; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   OrthoDB; 7156675at2; -.
DR   Proteomes; UP000027725; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027725}.
FT   DOMAIN          6..380
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          384..436
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          440..722
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          744..818
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   833 AA;  93169 MW;  65077CA4DED50C59 CRC64;
     MKTHVKVLVV GGGAVGCGVA YHLAKAGWDT LLVERDELTS GSTWHAAGLL PLFNMSYATT
     HIHKYSVDFY KSLEAETGLN AGFAVVGNLR MAQTEARMDE YRLYSSVAET AEVHHEFLTP
     AQMKERWPLL RTDDLKGALF HPQDGYINPA DVTQAMAKGA RQHGAEIARK LQVNAYRWTG
     SEWVVTLEKM VERGNRLVPS GEEIEIRAEH VVTCTGNHAQ RTARLLGIKI PAIPVEHQFI
     VTEPDPALMK WRAEGNPEHP VLRDADAKWY VREERGGWIL GPYERNAPAR FEYEVPDSFR
     ADLFQLDLDR IEEEYMSMIH RLPTSEEVGL KDDFNGPICY TPDGNPLVGP APGLRNMWLA
     EGFSFGITAA GGTGHYLAQL MTQGEAEIDM ASLDPRRYGA WMTTEYAARK NEEAYEHVFI
     LHHPDEEREA CRPLRTAPNY DRQIAEGAQM GQVNGWERPN YYGPKDAPAS FDHDSRSFRR
     GAWWDYAKAE AEAVRETAGL IDATAFTKHL VRGPGATAFL DLFTCNKLPK VGRINLTYAL
     TKAGTTRTEY TIVRLSEDEY YLISAGAWTD YDSDFLKQSI EDFRADGGDY VDCHDITTQW
     GVFALAGPNA RAILAEIVKD ADPATVLSNK RFPWLSMRNI ELGMCPVRAI RVAYTGELGW
     ELHHPIEMSR YLWDLLIAAG EKHGMKLVGA RAQNWLRQEK SYRAFGTELG RDATPQEAGL
     DRFIDLSKEF TGKQAMLDTG IRAKCVTLLI DGPEDSDPWG KEAIFDQGRK VGRLTSGGWS
     VAFGKQIGMG YVPPELSEPG TKLKVKIQLE EWDAVVAEDS PHDPSNARIR VDG
//