ID A0A074TJF1_9RHOB Unreviewed; 403 AA.
AC A0A074TJF1;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KEP70265.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:KEP70265.1};
GN ORFNames=DL1_19315 {ECO:0000313|EMBL:KEP70265.1};
OS Thioclava dalianensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Thioclava.
OX NCBI_TaxID=1185766 {ECO:0000313|EMBL:KEP70265.1, ECO:0000313|Proteomes:UP000027725};
RN [1] {ECO:0000313|EMBL:KEP70265.1, ECO:0000313|Proteomes:UP000027725}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DLFJ1-1 {ECO:0000313|EMBL:KEP70265.1,
RC ECO:0000313|Proteomes:UP000027725};
RA Lai Q., Shao Z.;
RT "The draft genome sequence of Thioclava dalianensis DLFJ1-1.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEP70265.1}.
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DR EMBL; JHEH01000007; KEP70265.1; -; Genomic_DNA.
DR RefSeq; WP_038064803.1; NZ_JHEH01000007.1.
DR AlphaFoldDB; A0A074TJF1; -.
DR STRING; 1185766.SAMN05216224_101521; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000027725; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:KEP70265.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000027725};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KEP70265.1}.
FT DOMAIN 5..233
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 280..402
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 359
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 389
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 403 AA; 42095 MW; 604F96BA8ED37743 CRC64;
MTDAYIYDAA RTPRGKGRKD GSLHEVSSVA LSAGLLNAVK ARNGLEGHAV EDVIWGNATQ
VMEQGGCLAR SAVLLSDLDE RIPGLSINRF CASGMEAVNL AANQIRGGAG QAYIAGGVEM
MGRVAMGSDG AAIAVDPSLA MKTYFVPQGI SADIIATEYG FSREDVDALA VESQKRAAEA
IADNRFAKSL VPVTDQNGLT ILDHDEYPRA GTTLETLGAL KASFKDMGEV MPGFDKVAML
KYPHLDHINH VHHAGNSSGI VDGAAAVLIG SKEFGEAHGL KPRARIRATA KIGTDPTIML
TGPVPVTEKI LADSGMSISD IDLFEVNEAF AAVVLRFMQA FQVDASKVNV NGGAIALGHP
LGATGAIIIG TLLDELERRD LSTGLATLCV ASGMGAATII ERV
//
