ID A0A074VG69_9PEZI Unreviewed; 1319 AA.
AC A0A074VG69;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 39.
DE SubName: Full=ABC multidrug transporter SitT {ECO:0000313|EMBL:KEQ57984.1};
GN ORFNames=M437DRAFT_89036 {ECO:0000313|EMBL:KEQ57984.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ57984.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ57984.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ57984.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL584863; KEQ57984.1; -; Genomic_DNA.
DR STRING; 1043003.A0A074VG69; -.
DR HOGENOM; CLU_000604_17_2_1; -.
DR OrthoDB; 1067095at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd18578; ABC_6TM_Pgp_ABCB1_D2_like; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF219; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..753
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 773..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 843..868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..895
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 953..979
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 991..1014
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..327
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 362..641
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 731..1019
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1073..1313
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 680..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1319 AA; 142592 MW; 5C3550338DAC7FCB CRC64;
MAGFIQKIGG YPRLLLAGDP TPRDIGTLLL GIVSSIAAGV PFPIIGILFG QLLDDFNAAT
CDQATDSGDG DQGSINNTIL IIFYLAIAQF VCIYVHLTCW TLNGARLAQR LRESYLQNLL
RQEPSFFDNL PPGEVASRLH GDIQTIRSGT AEKVGICLSS LSFFVTAYIV AFIKDWRLAA
ELLSLIPAYF IMSIVGSHYI EKYSGMVSEY AASAASIASE ALNNIMVVQA FGANARLEKK
FSDALRASEH EGIKKATAVG IQSGVLYFVA YSANGLAFWQ GSKRIADSVE GKSGGTTVGA
TFTVIFILIE ATLLLSQVAP FVHLFSAAVG SFNKLREDID RAPLIDGHTR SGLALPQTGA
GFEFTDVSFT YPSRPEITVL DKISLSIPAN KHTALVGLSG SGKSTIAGLV SRLYDPTDGR
ITFNGQDVRT LNARDLRSFM SLVQQEPSLL DRSLLENIAH GLINSSDPEH ARFRGILLGS
DLAEVATDVR DGTDLMVAAE KRGPVVVEIA TLVKSAATLA DADQFIVALQ QGYGTVVGSS
GRLISGGQKQ RVALARALVK NPAVLILDEA TASLDSRSEQ RIQRAINSIT SGRTVITIAH
RLATITAADN IVCMHKGHIL EQGTHSELMA NSGTYADMVK MQTLRNTSEA KNASADNISL
SDRTSTGDIE KKSLYDDTVE AEKAELSATE TPVRDSTEVE EPEELPAPPK SLWDLAKGYG
PALRPHILYI FVAFIGSVCV GGAFSGEAVI FGNTVGSLNP CHSASRIRNR GDFFGLMFFI
LAIIEFFANL VSWCGFGWVS EKVVYTVRVL SFRSLFEQDL QWHQSESRTP ALLLSYITRD
GNALAGFSGS VVGTLFSITV NLIAAIILTH IIAWRIALVC LALVPLLLGA GLMELHILGK
FEEKHETAYT KSVDIGVEAI TSIKTIASFS LEEEILRTYR RSLKGPRKDT LRVTLQASLC
QALTYFLGNC VNALAYWWGS KQILNGNYTQ TQFLIVVFSL LVGALLWSQM FALAPEISAA
RNAMARILSL IQIGKDKMAV HVRPLDISLE ENNIEALAET KTSHVSNNKA SSVQMKDVHF
SYPARPDVKV MNGLNIDIKP GQFAALVGPS GAGKSTVISL VERLYVPQSG SVLIDGLDVT
KTRDTSFRDS IALVPQESVL FEGSVEFNIG LGARPGHTVS KEEIIEACKL ANIHDVIAAL
PDGYDTLCGP NGSQFSGGQK QRLSIARALV RNPKLLILDE STSALDAESE RLLQEGLDKT
KAKGITVIAI AHRLHTIKKA NVIFLIEAGR CVDSGTHEQL LERSLDYRES VMHQTVATD
//
