ID A0A074VMS1_9PEZI Unreviewed; 564 AA.
AC A0A074VMS1;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=GTP cyclohydrolase II {ECO:0008006|Google:ProtNLM};
GN ORFNames=M437DRAFT_85249 {ECO:0000313|EMBL:KEQ61798.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ61798.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ61798.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ61798.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SIMILARITY: Belongs to the GTP cyclohydrolase II family.
CC {ECO:0000256|ARBA:ARBA00008131}.
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DR EMBL; KL584836; KEQ61798.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VMS1; -.
DR STRING; 1043003.A0A074VMS1; -.
DR HOGENOM; CLU_029639_1_0_1; -.
DR OrthoDB; 46806at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003935; F:GTP cyclohydrolase II activity; IEA:InterPro.
DR GO; GO:0009231; P:riboflavin biosynthetic process; IEA:InterPro.
DR CDD; cd00641; GTP_cyclohydro2; 1.
DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR InterPro; IPR022163; GTP_CH_N.
DR InterPro; IPR032677; GTP_cyclohydro_II.
DR InterPro; IPR000926; RibA.
DR InterPro; IPR036144; RibA-like_sf.
DR PANTHER; PTHR47259; -; 1.
DR PANTHER; PTHR47259:SF2; URACIL-REGULATED PROTEIN 1; 1.
DR Pfam; PF12471; GTP_CH_N; 1.
DR Pfam; PF00925; GTP_cyclohydro2; 1.
DR SUPFAM; SSF142695; RibA-like; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672}.
FT DOMAIN 98..289
FT /note="GTP cyclohydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12471"
FT DOMAIN 327..445
FT /note="GTP cyclohydrolase II"
FT /evidence="ECO:0000259|Pfam:PF00925"
FT REGION 57..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 61768 MW; 3A083FAB112B58B0 CRC64;
MNGASGDAAI LQEILASLKT IQQENTHLAA AVDAINGRVN ILAGVKQVKD MTVDPTAVKH
NKQPPADPVV PPLSENTPSS PDLSAMSGSG RRSSVTSKII LTSYPGQAGV DPLPMDWGNK
DPSLRGPVVV SRNPSSIRRR NAIGAHGGSY AIYNALAVAS KNLNTDHRPD FTNTEPAANI
GPFPQWSDPK KIVAMDPLGH LSPWLFKDII QKEDVDIRPT IAITKAHMRV PELEESVKAG
RLVPDGKICL NATGELAVTK FAVEPVWYLP GVAERFGIDE GTLRRSLFEY TGGSYPELIT
RGDIKTFLPP IGGLTVYCFG DPAKMSDPSV KLALRIHDEC NGSDVFGSDI CTCRPYLTFG
IEEAVKEAQN GGSGVVIYFR KEGRALGEVT KYLVYNARKR GADRASEYFK RTENIAGVKD
MRFQALMPDI LHWLGITKID RMLSMSNMKG VLRFKGMLTK SPRPKLRIDS SSPQYTLHDA
IVEQGIPIHE RVELPDEMIP ADSRVEIDAK IAAGYFTNGN VMTMDELSNV QGRAWEDVDK
LGSYCFSNLS LVHIKESPER FMHA
//
