ID A0A074VSB4_9PEZI Unreviewed; 430 AA.
AC A0A074VSB4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=3-phytase {ECO:0000256|ARBA:ARBA00012632};
DE EC=3.1.3.8 {ECO:0000256|ARBA:ARBA00012632};
GN ORFNames=M437DRAFT_46933 {ECO:0000313|EMBL:KEQ63625.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ63625.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ63625.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ63625.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC {ECO:0000256|ARBA:ARBA00005375}.
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DR EMBL; KL584831; KEQ63625.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VSB4; -.
DR STRING; 1043003.A0A074VSB4; -.
DR HOGENOM; CLU_020880_3_2_1; -.
DR OrthoDB; 2404758at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0016158; F:3-phytase activity; IEA:UniProtKB-EC.
DR CDD; cd07061; HP_HAP_like; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR033379; Acid_Pase_AS.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR016274; Histidine_acid_Pase_euk.
DR PANTHER; PTHR20963:SF56; ACID PHOSPHATASE-RELATED; 1.
DR PANTHER; PTHR20963; MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR PIRSF; PIRSF000894; Acid_phosphatase; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000894-2};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..430
FT /note="3-phytase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001700897"
FT ACT_SITE 62
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT ACT_SITE 321
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-1"
FT DISULFID 51..370
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 244..259
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
FT DISULFID 393..401
FT /evidence="ECO:0000256|PIRSR:PIRSR000894-2"
SQ SEQUENCE 430 AA; 47058 MW; B364643AF0B95B32 CRC64;
MLSLSSLAQL TLVPAAAAQA FNLYEHLGNL SPYFTPPNTP PSLLSGIPES CSVDRAFLVH
RHGSRQPISS ELPTIQNLSY YINNNTALFK NPQGQLPSEF SFLKSGWSSG FTLNNLSAPG
RQQLFDHGVA FRLDYPSLYT DTVLAGDQDR VVESAQWFMD GYYGRYVEDV AVLNKIAEDN
LTISWITSTD TCKTWEYSSG NDLVTDWGKV YLPSIATRMN KALSSAYPGV NFTAQHAHGA
LWACAYGTAV YGIGRSPWCA VFKPQEILGF EYELDLLMRG AFGYGLPNDQ GPVLGSLLVS
NVTTFLQSST GQNLSLNFAH DTTIDLGLTA LGLAYDQQYP ATGPPNPSRN WRTSTQVPFA
AQMLFKRLSC SNNETRIQLE LNGANFDLSP VGCTSDYYGT CKLADFVATK HVQTAMNITD
GDATWNAACL
//
