ID A0A074W7B7_9PEZI Unreviewed; 666 AA.
AC A0A074W7B7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=FAD/NAD(P)-binding domain-containing protein {ECO:0000313|EMBL:KEQ68758.1};
GN ORFNames=M436DRAFT_57763 {ECO:0000313|EMBL:KEQ68758.1};
OS Aureobasidium namibiae CBS 147.97.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043004 {ECO:0000313|EMBL:KEQ68758.1, ECO:0000313|Proteomes:UP000027730};
RN [1] {ECO:0000313|EMBL:KEQ68758.1, ECO:0000313|Proteomes:UP000027730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 147.97 {ECO:0000313|EMBL:KEQ68758.1,
RC ECO:0000313|Proteomes:UP000027730};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000256|ARBA:ARBA00004137}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004137}; Intermembrane side
CC {ECO:0000256|ARBA:ARBA00004137}.
CC -!- SIMILARITY: Belongs to the NADH dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00005272}.
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DR EMBL; KL584726; KEQ68758.1; -; Genomic_DNA.
DR RefSeq; XP_013422910.1; XM_013567456.1.
DR AlphaFoldDB; A0A074W7B7; -.
DR STRING; 1043004.A0A074W7B7; -.
DR GeneID; 25412537; -.
DR HOGENOM; CLU_021377_1_1_1; -.
DR OrthoDB; 48029at2759; -.
DR Proteomes; UP000027730; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003954; F:NADH dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006116; P:NADH oxidation; IEA:InterPro.
DR Gene3D; 3.50.50.100; -; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR045024; NDH-2.
DR PANTHER; PTHR43706; NADH DEHYDROGENASE; 1.
DR PANTHER; PTHR43706:SF50; NADH DEHYDROGENASE (UBIQUINONE)-RELATED; 1.
DR Pfam; PF00036; EF-hand_1; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000027730};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..529
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 666 AA; 74461 MW; 8FB7934F9B0E4C90 CRC64;
MPAPASLARS AIIPQLNHVR RQSTNTDPPP KSPAATPVQR SRVLRFLWRG FTLLGVFVVI
SGVLVVAFFA FDATTYKENA DTVDISVSEL ALNPRRGGPK NLPIAEHLLD DDESPEKKAQ
KHKPKLVILG TGWGSVALLK QLNPDDYHVT VVSPSNYFLF TPMLPSATVG TLELRSLVEP
VRRIISRVKG HFLKATAEDV DFSNKLVEVS AINPDGSKQN FYLPYDKLII GVGSMTNPHG
VKGLEYCNFL KDITDARLIR NQIVRNLEAA SLPSTPDEER RRLLSFVVCG GGPTGVEFAA
ELFDMLNEDL CNYYPRILRN EISVHVIQSR GHILNTYDET LSKYAEARFA KDAVDILTNS
RVKEVQKDKI LFTQKDENGK TVTKEIPMGF CLWSTGVAQT EFSKKLAEKL GENQTNRHAL
ETDTHLRLVG APLGDVYAIG DCSTVQNNVS DHIVSFLRTV AWEKGKDPEK MLIGYGDWRG
VAKRVKQRFP QAAEHLKRLD KLFEQYDKDK SGTLDFSELQ ELLKQIDGKM TSLPATAQRA
NQQGIYLGRK LNKLSQAAPG MELNQLDYGD IDDAVYKTFS YTNMGSLAYV GNAAIFDFGG
MNFAGGLVAV YLWRAVYFSQ SVSLRTRILL AMDWTKRALF GRGKQMMKLQ RRKNNVLTSK
TDLMNF
//
