ID   A0A074WB87_9PEZI        Unreviewed;       886 AA.
AC   A0A074WB87;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Probable endonuclease LCL3 {ECO:0000256|ARBA:ARBA00013404};
DE   AltName: Full=Probable endonuclease lcl3 {ECO:0000256|ARBA:ARBA00014651};
GN   ORFNames=M437DRAFT_38020 {ECO:0000313|EMBL:KEQ67152.1};
OS   Aureobasidium melanogenum CBS 110374.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX   NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ67152.1, ECO:0000313|Proteomes:UP000030672};
RN   [1] {ECO:0000313|EMBL:KEQ67152.1, ECO:0000313|Proteomes:UP000030672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ67152.1,
RC   ECO:0000313|Proteomes:UP000030672};
RX   PubMed=24984952;
RA   Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA   Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA   Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT   "Genome sequencing of four Aureobasidium pullulans varieties:
RT   biotechnological potential, stress tolerance, and description of new
RT   species.";
RL   BMC Genomics 15:549-549(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
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DR   EMBL; KL584824; KEQ67152.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A074WB87; -.
DR   STRING; 1043003.A0A074WB87; -.
DR   HOGENOM; CLU_005966_1_0_1; -.
DR   OrthoDB; 375531at2759; -.
DR   Proteomes; UP000030672; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR   CDD; cd00175; SNc; 2.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 2.40.50.90; -; 5.
DR   InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   InterPro; IPR002999; Tudor.
DR   PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR   PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00565; SNase; 3.
DR   Pfam; PF00567; TUDOR; 1.
DR   PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR   SMART; SM00318; SNc; 4.
DR   SMART; SM00333; TUDOR; 1.
DR   SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS50830; TNASE_3; 4.
DR   PROSITE; PS50304; TUDOR; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022759};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          2..142
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          166..308
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          318..455
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          484..617
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50830"
FT   DOMAIN          702..762
FT                   /note="Tudor"
FT                   /evidence="ECO:0000259|PROSITE:PS50304"
FT   REGION          622..647
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   886 AA;  98815 MW;  4F4D535540D09F16 CRC64;
     MALMEAKVKS VLSGDTLVLH NIKNPSQERT LSLAFVSAPR IRREGDEPGA FQSRDFVRKL
     CVGKVVRFAV LYNIPTPSPR DYGVIILQSG QHLLDLVVRE GLVKLRDDAG KKEDTPQGTE
     LLERLQALES HAKVDEKGLW NPDQQRIDNV QDLSDPRAFS EAYKGQPIDA IVERVLSADR
     LICRLLVQPT KHTQTIVLLA GVRAPATKRI NPSDQSEQPA EPFGTEAHRF VEERLLQRGV
     QVRILGVSPN NLLVGEVRHP MGSIAEFLLK AGLARCTDHH STWLGPEMAK LRQAERYARD
     NKLGLFEGHV SQRSAGTGQI EATVSRVFSA DTLYLRNKAG AEKRVNLSSV RQPKPSDPKQ
     SPFGAEAKEF LRKRLIGKHV KVTIDGKRPA TEGFDEREMA TVTLNDENVS LMLVEQGYAS
     VIRHRMDDTD RSPIYDDLLA AEEAAQSAGK GMWNPKPPKK TEYVDYSASV DQAKRQLTLL
     SRQRKVPAVV DFVKSGSRFT VLVPRENAKL TFVLSGISAP RSARNPNEKG EPFGQEAHEF
     ANRRCQQRDV EIDVEGTDKV GGFIGQLYVN RESFAKLLVE EGLASVHAYS AEKSGNANEL
     FAAEQRAKEA RRGMWHDWDP SKEAAEEGEE YDASAGTAGM NGDAPAERRK DYRDVVVTNI
     DPTNARIKIQ EIGTGTAALT DLMNSFRSFH ISSSANKPLE QAPKAGDFVS ARFSEDNEWY
     RARVRRNDRE NKTSEVVYID YGNSETIPWS RLRALDPTRF GVQKLRAQAL DATLSFLQFP
     TAPEYLREAV NIISDCTADR QLVANVDYID PREGTLHVTL FDPKQSDSLN ESVNADIISE
     GFAMVPKKLK AWERAAGDVL ADLQAREAEA KERRLGQWEY GDLTED
//