ID   A0A074WRB9_9PEZI        Unreviewed;       987 AA.
AC   A0A074WRB9;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Ribonuclease R {ECO:0000313|EMBL:KEQ72252.1};
GN   ORFNames=M436DRAFT_49555 {ECO:0000313|EMBL:KEQ72252.1};
OS   Aureobasidium namibiae CBS 147.97.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX   NCBI_TaxID=1043004 {ECO:0000313|EMBL:KEQ72252.1, ECO:0000313|Proteomes:UP000027730};
RN   [1] {ECO:0000313|EMBL:KEQ72252.1, ECO:0000313|Proteomes:UP000027730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 147.97 {ECO:0000313|EMBL:KEQ72252.1,
RC   ECO:0000313|Proteomes:UP000027730};
RX   PubMed=24984952;
RA   Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA   Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA   Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT   "Genome sequencing of four Aureobasidium pullulans varieties:
RT   biotechnological potential, stress tolerance, and description of new
RT   species.";
RL   BMC Genomics 15:549-549(2014).
CC   -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC       {ECO:0000256|ARBA:ARBA00005785, ECO:0000256|RuleBase:RU003901}.
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DR   EMBL; KL584712; KEQ72252.1; -; Genomic_DNA.
DR   RefSeq; XP_013426218.1; XM_013570764.1.
DR   AlphaFoldDB; A0A074WRB9; -.
DR   STRING; 1043004.A0A074WRB9; -.
DR   GeneID; 25411090; -.
DR   HOGENOM; CLU_002333_5_0_1; -.
DR   OrthoDB; 945235at2759; -.
DR   Proteomes; UP000027730; Unassembled WGS sequence.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR   CDD; cd09862; PIN_Rrp44-like; 1.
DR   Gene3D; 2.40.50.690; -; 1.
DR   Gene3D; 2.40.50.700; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR041505; Dis3_CSD2.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR001900; RNase_II/R.
DR   InterPro; IPR022966; RNase_II/R_CS.
DR   InterPro; IPR033771; Rrp44_CSD1.
DR   InterPro; IPR033770; RRP44_S1.
DR   InterPro; IPR003029; S1_domain.
DR   PANTHER; PTHR23355:SF35; EXOSOME COMPLEX EXONUCLEASE RRP44; 1.
DR   PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR   Pfam; PF17849; OB_Dis3; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   Pfam; PF00773; RNB; 1.
DR   Pfam; PF17216; Rrp44_CSD1; 1.
DR   Pfam; PF17215; Rrp44_S1; 1.
DR   SMART; SM00670; PINc; 1.
DR   SMART; SM00955; RNB; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 3.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
DR   PROSITE; PS01175; RIBONUCLEASE_II; 1.
DR   PROSITE; PS50126; S1; 1.
PE   3: Inferred from homology;
KW   Exosome {ECO:0000256|ARBA:ARBA00022835};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027730};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          892..987
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000259|PROSITE:PS50126"
SQ   SEQUENCE   987 AA;  111634 MW;  B490CBAEED5D7B24 CRC64;
     MTSLKRSYAA DSAAPNLSSK VYIRSTKSGK VQKIVRELYL REDIPCSSRL CARCLEIAPT
     DYHNKVAPFV LSETPGGTKS FPNGHYIIPD TNAFLTGMDL FELETAFFDV IVLQTVLEEV
     KNRSLPLYHR LISLTKNDSK RFYVFFNDFR LQTYVVRQDK ETINDRNDRA VRRAVKWYAD
     HLDEAVSKRK SIRCPSIVMI SDDRDNIRKA KNDGITGLSL RDYVSGLDES ERLLDMVSAG
     QEQRVGKQTK GELLYPDYLS VSKMITGVKA GTMHQGTFNV SPYNYLEGSV FVPAFDKPLL
     IIGRENSNRA ISGDIVVVEV LPKDQWKAPS SKILEEEVVN KNDNADADEG EAVITQQEKR
     ALQEEVKKTH GKSAEGRPQP TARVVGIIKR NWRQYVGHVD KDSVKSSTKQ SRAQQTVFLI
     PMDKRIPKIR IRTRQAGDLL GKRLLVTIDA WDRESRYPVG HFVRSLGELE TKGAETEALL
     LEWDVQYRPF PKTVLDCLPA EGHDWKVPTD MSDPGWNKRR DLRDLLICSI DPPGCVDIDD
     ALHARTLPNG NIEVGVHIAD VSNFVKPNNA MDQEASLRGT TVYLVDKRID MLPMLLGTDL
     CSLKPYVERF AFSVIWELTP EADIVRADYT KSVIKSREAF AYEQAQIRVD DQSQQDDLTN
     GIRMLMMLSK KLKKKRMDAG ALNLASPEVR VQTESETADP ADVQTKQHLD TMSLVEEFML
     LANTSVAARI YEAYPQTALL RRHAAPPKTN FEELSNQLRV KRGMELRTDS SKALADSLDT
     CVEPSEPFFN TLVRIMATRC MMSAEYFCSG TQAYPEFRHY GLASEIYTHF TSPIRRYADL
     EAHRQLAAAI DYEPLDASLL SKAKLEGVCK NINVRHRNAQ QAGRASVEYY VGQALKGRVV
     DEDGFIMRVF SNGIVVFVPR FGIEGLIRLR DLATPEPESE FDTENYILKI KGEGIDRNVE
     LFEKIKVRIS DEAEESTGKR KVKLSLL
//