ID A0A074X9J0_AURPU Unreviewed; 669 AA.
AC A0A074X9J0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=histone deacetylase {ECO:0000256|ARBA:ARBA00012111};
DE EC=3.5.1.98 {ECO:0000256|ARBA:ARBA00012111};
GN ORFNames=M438DRAFT_399901 {ECO:0000313|EMBL:KEQ80404.1};
OS Aureobasidium pullulans EXF-150.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043002 {ECO:0000313|EMBL:KEQ80404.1, ECO:0000313|Proteomes:UP000030706};
RN [1] {ECO:0000313|EMBL:KEQ80404.1, ECO:0000313|Proteomes:UP000030706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-150 {ECO:0000313|EMBL:KEQ80404.1,
RC ECO:0000313|Proteomes:UP000030706};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SIMILARITY: Belongs to the histone deacetylase family. HD type 1
CC subfamily. {ECO:0000256|ARBA:ARBA00006457}.
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DR EMBL; KL584998; KEQ80404.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074X9J0; -.
DR STRING; 1043002.A0A074X9J0; -.
DR HOGENOM; CLU_007727_0_1_1; -.
DR OrthoDB; 1327607at2759; -.
DR Proteomes; UP000030706; Unassembled WGS sequence.
DR GO; GO:1902494; C:catalytic complex; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd10004; RPD3-like; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR003084; His_deacetylse_1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF13; HISTONE DEACETYLASE HDAC1; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR PRINTS; PR01271; HISDACETLASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000030706}.
FT DOMAIN 42..332
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 392..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..429
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..452
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..489
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..661
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 669 AA; 73577 MW; 52843364357CFE33 CRC64;
MANSAQYGPP LDPPRATNGG RPKKVAYFYD SDVGNYAYNA GHPMKPHRIR MAHSLIMNYG
LYKKMEIYRA KPASKYEMTQ FHTDEYVDFL SKVTPDNMDS YAKEQGKYNV GDDCPVFDGL
FEYCGISAGG SMEGAARLNR QKCDVAVNWA GGLHHAKKSE ASGFCYINDI VLGIIELLRF
KSRVLYIDID VHHGDGVEEA FYSTDRVMTC SFHKYGEYFP GTGELRDIGV GNGKNYAVNF
PLRDGMDDVA YKSVFEPIIA KIMEFFRPDA VVLQCGGDSL SGDRLGCFNL SMRGHANCVK
YVKSFNLPTL VLGGGGYTMR NVARTWAYET GQLVGQEMGP ELPYTDYYEY YSPDFELDVR
PSNMDNANSP EYLEKIKLQV FENLSRTRFA PSVQMTDVPR SPLVVQPNEN DPDNEGDTED
LDEREQRLDD KDDDENPDSR YTERKWDARI ERDDEFEDSD DEEMDALLGV KKQPGAEPRR
PRITDHKNPY ADMAEGSLAE SGTTTPLDTT LPPAAAQADQ MVVDRAQAAN AAVGDAIMAA
KASEDPHAVQ PAMGEEVASN GTQRARSPQN APSTTAQAPA AEPEDVEMGE DDVAEPPANA
PNSNNTQAGA GPTATPPPDP TVAETTTTAP EDVEMGDGAA EAKEEGRQER DAEDVQGEMK
REGEAGGIN
//
