ID   A0A074XRT5_AURPU        Unreviewed;      1395 AA.
AC   A0A074XRT5;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Cullin-domain-containing protein {ECO:0000313|EMBL:KEQ88160.1};
GN   ORFNames=M438DRAFT_402115 {ECO:0000313|EMBL:KEQ88160.1};
OS   Aureobasidium pullulans EXF-150.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX   NCBI_TaxID=1043002 {ECO:0000313|EMBL:KEQ88160.1, ECO:0000313|Proteomes:UP000030706};
RN   [1] {ECO:0000313|EMBL:KEQ88160.1, ECO:0000313|Proteomes:UP000030706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-150 {ECO:0000313|EMBL:KEQ88160.1,
RC   ECO:0000313|Proteomes:UP000030706};
RX   PubMed=24984952;
RA   Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA   Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA   Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT   "Genome sequencing of four Aureobasidium pullulans varieties:
RT   biotechnological potential, stress tolerance, and description of new
RT   species.";
RL   BMC Genomics 15:549-549(2014).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KL584975; KEQ88160.1; -; Genomic_DNA.
DR   STRING; 1043002.A0A074XRT5; -.
DR   HOGENOM; CLU_254666_0_0_1; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000030706; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF126; CULLIN 4, ISOFORM A; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030706};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          1013..1268
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          494..594
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1124..1151
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        503..520
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        540..594
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1395 AA;  157102 MW;  45E0B200EE92A99E CRC64;
     MSIPQSLNIS TALCLIKSKP KHLTVQEYIR ALRPHIRTIH SNGQVYRQID HSAFWQGQHD
     GLKANLEKER DATFILKQQN DALVSQVTQL LARSKPGRKR KVEQEEPEKV KKLKAGTIAI
     TEFGLAADIG PVIKAMRHIH RVQTLCRGRM WSTDSNELAY NLIQTMQAME NIIDPLANKK
     HSADSCKQTI TAVARTCITV FHGLKRMESL NSNDGFPSHV VHACVCFFGI LFTSIENAAR
     LQVEPKQPDR GTAVLQALST LANSLINILR GSSPNCPSHA EILEGATYDL LHRLGETTHE
     LLMDGPQHDD IEHEVQKLPL PDDKRLDPVR QTAMRTMLTA APFLLDCLRK ALIGAQNQPL
     AAFARLKLQR TLVDRIFGPG TRGPNASEDV LGLPEVFGEP PMAANPIKKE DIQTKTDQFE
     EEIWALVGWD ILALLQREDK SGRICFTCRH CFDTYNKLFE MSCSHDLALD VFFINLESAG
     SGCKVVEQQS HDEKVLQRGH SCTPASMPPS ISSLPAGDRS PSSSPPHPPA RKRKRPSAAT
     TAAATPSASS QPPASLGRQQ SIQNLFADQA SAAASPSTAI DSSPNRKKVK NQPFNMQSDM
     YSFSSKVIGG NLPAATSITR RTPGRLNKGF TPKAGTTKLV VKTLKPQPAW DGNKYFEDIW
     AQLDRALNVI FTQAPVDFSM EELYRGVENL CRQKRAEEIY VKLSSKCKAH VRGPMKTSLL
     SKQRQSNVQV LDDVLGAWTA WSKQMTVIRC IFYYMDRSYL LQTSRGSLQD VTIKIFRDNI
     FEDPSLKLAI IDGACDLISA DRAGQELEPS HLSQAITMFH DLATYSTSFE PRMLASAQRY
     VVEWANEKSA EKPLPEYVNE AVTFMTKEIE RCELFGLDQS TRRDLLALLE EHIIKEKVDY
     LTNQDSVADL LDDYAVKDLE QLHSLLQRRR LGSKIKPAFA RWVEDTGSQI VFDDKNDTQM
     VVRLLSLKTR LDHIWRTSFH RSEELGHALR ESFETFINKT KKAAATHGTD NSRTGEMIAK
     YVDQLLRGGA KVIPTDLTLH ARDNAGKEEF DDNEAMDEDS EVNAQLDQVL DLFRFVHGKA
     VFEAFYKKDL ARRLLMGRSA SADAERSMLA RLKTECGAEF THNLEQMFKD VELAREEMSS
     YKSRMEEREE RPKVDLNVNV LSAAAWPTYP DVPVVIPADI KTAIDEYERH YKSKHSGRKL
     DWKHSLAHCQ MKAKFAKGTK ELVVSSFQAI ILLLFNGIDA STHLTYDFIK SESGLPEAEV
     NRTLQSLACA KLRPLAKHPK GREISPTDTF TIDPSFWHDK YRVKINQVQL KETKEENKET
     HERVAADRNF ECQAAVVRVM KSRKTIGHSE LIAEVITATR SRGVLDVKDI KKNIDRLIEK
     DYMEREEGNM YSYIA
//