ID   A0A074YHI4_AURSE        Unreviewed;       850 AA.
AC   A0A074YHI4;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=alpha-L-fucosidase {ECO:0000256|ARBA:ARBA00012662};
DE            EC=3.2.1.51 {ECO:0000256|ARBA:ARBA00012662};
GN   ORFNames=AUEXF2481DRAFT_77967 {ECO:0000313|EMBL:KEQ97150.1};
OS   Aureobasidium subglaciale (strain EXF-2481) (Aureobasidium pullulans var.
OS   subglaciale).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX   NCBI_TaxID=1043005 {ECO:0000313|EMBL:KEQ97150.1, ECO:0000313|Proteomes:UP000030641};
RN   [1] {ECO:0000313|EMBL:KEQ97150.1, ECO:0000313|Proteomes:UP000030641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-2481 {ECO:0000313|EMBL:KEQ97150.1,
RC   ECO:0000313|Proteomes:UP000030641};
RX   PubMed=24984952;
RA   Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA   Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA   Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT   "Genome sequencing of four Aureobasidium pullulans varieties:
RT   biotechnological potential, stress tolerance, and description of new
RT   species.";
RL   BMC Genomics 15:549-549(2014).
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 29 family.
CC       {ECO:0000256|ARBA:ARBA00007951}.
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DR   EMBL; KL584754; KEQ97150.1; -; Genomic_DNA.
DR   RefSeq; XP_013345982.1; XM_013490528.1.
DR   AlphaFoldDB; A0A074YHI4; -.
DR   STRING; 1043005.A0A074YHI4; -.
DR   GeneID; 25371444; -.
DR   HOGENOM; CLU_002934_4_1_1; -.
DR   InParanoid; A0A074YHI4; -.
DR   OMA; HRDTYGE; -.
DR   OrthoDB; 2955544at2759; -.
DR   Proteomes; UP000030641; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KEQ97150.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030641};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..850
FT                   /note="alpha-L-fucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001704427"
SQ   SEQUENCE   850 AA;  92681 MW;  F7FAF692E83F2BF3 CRC64;
     MSALSYPKLA LLGLVPLALG QGGLVINPKN AGLQQAGSHA SSVPIDLSGM VNNRAFAMTP
     GDADFDGIHS GYPAQFLPDS NFTYAGVNYI FPQYKQTGDD NVLAQGQIVT PSQGRYSSIS
     MLVAAESAVA TGYVNVTYTD NTTSSSPILV DPFWSWPYPY GGDIVFPYYL TNSSVDYNRS
     MIYQSVNWLD STKEVSSIVL PNVTSGAATG PGGAAQNTRL HIFAVSLVTA TGSGISLEIQ
     QARSTQLWME GTNKTQIFEA VVVNTGNDWI LANNSVKVTV EAAGVTTVHP GIINRLRPGD
     RATVRIGVIN AGGTQPGTSG EATLRITGAG VQTSSSFSAT FGISTYEATY ESIYSHESPP
     WYTGGKYGIF IHWGVYAVPG WGNSGKKEQY AEWYWWYMNQ GNDSSNSADF YEYNLETYGQ
     DHVYDDFIQN FTTEHYNPKE WVDLFADAGA QYFVQVSKHH EGYALFDIPA NITMRTSVAQ
     VPHKNLLQML FDAAEQYQPH LHKATYFSLP EWFHPDYKKY GFGEADGAGW PGGNATNPYT
     NETLAYTGYV PVNDFVSDLI LPEMQILAQM GTEIMWCDIG GPNLTAEFSA EYFNNMAAQG
     KQVLINNRCG LPGDFDTPEY ARYEAVQMRK WESNLGMDPF SYGYNRATPI SAYIKPADIV
     ASLIDITSKN GNFLLDIGPQ ANGTIVDIEK QNLRAAGKWI KSHGEAIFNT TYWFITPEEG
     DTVRFTQTPN AFYILTLYPP NSTLVLDSPV PYVTGDQVTV VGGNMSGSVV PSKLLSNGSL
     ELTISDAVIA GDEYSWVFKI MFGGVNTMGN STYTGSAPPA QQTTNDAGMS SADWTKFIPS
     AVLGIVLWLV
//