ID   A0A074YXK6_9TREM        Unreviewed;       493 AA.
AC   A0A074YXK6;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Peptidase C13 family protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=T265_11816 {ECO:0000313|EMBL:KER19398.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER19398.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER19398.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
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DR   EMBL; KL597222; KER19398.1; -; Genomic_DNA.
DR   RefSeq; XP_009176855.1; XM_009178591.1.
DR   AlphaFoldDB; A0A074YXK6; -.
DR   MEROPS; C13.007; -.
DR   GeneID; 20325984; -.
DR   KEGG; ovi:T265_11816; -.
DR   CTD; 20325984; -.
DR   OrthoDB; 2951493at2759; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1460; -; 2.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR12000:SF42; LEGUMAIN; 1.
DR   Pfam; PF01650; Peptidase_C13; 2.
DR   PIRSF; PIRSF019663; Legumain; 4.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT   ACT_SITE        202
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        243
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   493 AA;  56839 MW;  902E340B4E9C2FE3 CRC64;
     MKLQVTLDAM RHCSILIALL FCLVHATRLE AIGFQNWSFI LNNNPSKNWV ILAAGSNSWI
     DYRHQDLHII AALRIVSYSI IESDTHCTQR RRKFIQNKSP ERNTNRIYEQ FISFCSTYML
     TSPKTRCRIS FFYFRNPFKG KVFHDYEHED VYGGVVIDYR GNEVNSDTFV RALKGDKRLE
     RQGKKVLKSG PDDYVFIYYS DHGAPYSIKF PIGSLDALEF NDILACMYLN KMYKKMVVYM
     DSCYSGSLFY DILPTIAGTP YGFSLFLSLT RVQKDIKKRT LDQQYEEVKK RTKQSHVMKY
     GEKEMGSLPV GKFQGHYDLL TNRNDGAIAP TAADRKPSSR AHLFSLSRSM MDATTKEVHE
     RARRKLHRAL QSIILVAASG SRQKYPIACW LHVPEVSYSL LNSSHICSYI FFQLGHIVKQ
     TFRDIVEDAT THHKPTVKGL SKRDELICFK AVFDQFQSHC FTIHQVGCPK GARCHACKHV
     FTLLTNTFTL HVT
//