ID   A0A074Z6E9_9TREM        Unreviewed;       603 AA.
AC   A0A074Z6E9;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=Pescadillo homolog {ECO:0000256|HAMAP-Rule:MF_03028};
GN   ORFNames=T265_14797 {ECO:0000313|EMBL:KER22726.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER22726.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER22726.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for maturation of ribosomal RNAs and formation of
CC       the large ribosomal subunit. {ECO:0000256|HAMAP-Rule:MF_03028}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC       Rule:MF_03028}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03028}.
CC   -!- SIMILARITY: Belongs to the pescadillo family. {ECO:0000256|HAMAP-
CC       Rule:MF_03028}.
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DR   EMBL; KL596883; KER22726.1; -; Genomic_DNA.
DR   RefSeq; XP_009173542.1; XM_009175278.1.
DR   AlphaFoldDB; A0A074Z6E9; -.
DR   STRING; 6198.A0A074Z6E9; -.
DR   GeneID; 20328963; -.
DR   KEGG; ovi:T265_14797; -.
DR   CTD; 20328963; -.
DR   OrthoDB; 169151at2759; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-UniRule.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-UniRule.
DR   CDD; cd17709; BRCT_pescadillo_like; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 1.
DR   HAMAP; MF_03028; Pescadillo; 1.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR010613; PES.
DR   PANTHER; PTHR12221; PESCADILLO - RELATED; 1.
DR   PANTHER; PTHR12221:SF6; PESCADILLO HOMOLOG; 1.
DR   Pfam; PF06732; Pescadillo_N; 1.
DR   SUPFAM; SSF52113; BRCT domain; 1.
DR   PROSITE; PS50172; BRCT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|HAMAP-Rule:MF_03028};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517, ECO:0000256|HAMAP-
KW   Rule:MF_03028};
KW   rRNA processing {ECO:0000256|ARBA:ARBA00022552, ECO:0000256|HAMAP-
KW   Rule:MF_03028}.
FT   DOMAIN          317..409
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   REGION          503..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..569
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..603
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   603 AA;  68582 MW;  8820E771F6D10C29 CRC64;
     MTKLKKKNKK GLVAAFLSQK QAMRRLQLSL PNFRRLCILK GVYPVEPSNR KKVGKGNSQP
     RVFYHSKDIA FLAHEPLIEK FRRLRVYQLK LKKARERRDK DKEFRIRVNK PRYTLHHVVK
     ERYPTCQDAL NDLSDSLNLI FLFARLPRLT QFSPSLIALS RRLCVEFLNF VVATRAIRKA
     FISIKGFYIQ ADISGTLVVW VIPHSSVTHT PSDVDYRILA NCLEFDTTLV GSLLCHLYRQ
     HGLLYPPKLS VHVDPDPTSY YCGQNENYFE LLSCLSYPIR RTEDVAGEDV HSEGLSELQA
     IDDQVAKAVN KQLEVQRIRK LFDGKRIFLM REVPREVICL IVRSCGGECS WDKTVGPAST
     FTEEDPSIDY QVVDRPMSEM KVTRYYVQPQ WVFDSLNAGR LLPAQDYLPG SSLPPHLSPF
     AAGSGLTEIL GEIGEGSVSQ RGGLVGVAPG FGDGASLYRP PEADYLAGLV SLAKLRGPTI
     QASMEPNATV DEHQMELDDV HSALDNTDNS FGSHKKKEKA NSKLRKPAKG EEPIVTPGRL
     ESKESKRMKE QAEANAERKL REMLLPKKHR NAYKKMVHSI KRREKEVRNL TDKRRAIDSR
     RET
//