ID A0A074Z7R8_9TREM Unreviewed; 634 AA.
AC A0A074Z7R8;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
DE Flags: Fragment;
GN ORFNames=T265_15599 {ECO:0000313|EMBL:KER19270.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER19270.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER19270.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL597263; KER19270.1; -; Genomic_DNA.
DR RefSeq; XP_009176985.1; XM_009178721.1.
DR AlphaFoldDB; A0A074Z7R8; -.
DR STRING; 6198.A0A074Z7R8; -.
DR GeneID; 20329764; -.
DR KEGG; ovi:T265_15599; -.
DR CTD; 20329764; -.
DR OrthoDB; 5395251at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 6.
DR Gene3D; 2.10.25.10; Laminin; 11.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF12661; hEGF; 1.
DR PRINTS; PR00010; EGFBLOOD.
DR PRINTS; PR01983; NOTCH.
DR SMART; SM00181; EGF; 12.
DR SMART; SM00179; EGF_CA; 9.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 10.
DR PROSITE; PS01186; EGF_2; 8.
DR PROSITE; PS50026; EGF_3; 11.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 62..98
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 140..179
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 181..217
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 219..255
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 257..294
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 351..383
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 385..424
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 426..462
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 497..548
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 550..590
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 592..631
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 88..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 169..178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 207..216
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 245..254
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 284..293
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 373..382
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 414..423
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 452..461
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 580..589
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 621..630
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KER19270.1"
SQ SEQUENCE 634 AA; 68117 MW; D76CADB10BACDE2D CRC64;
HVRTLQQPSC PSVDLNPFSI SQFTPQRHST PAGCDYSMFP QHCTCVLLQL VLLCYAEDAQ
SRVLDCYQVP CQNGGECIGS PDNSTCKCPP GFSGFWCENP GQCGNGPCHP HVSSTSIQST
PSYKYGTCPS GWTGLNCDED VDECSIGHRS PCEHEGVCMN TPGDFVCRCR EGFTGARCEI
EILECATSPC LNGGSCVEGI GNYHCICPPG FEGDNCEHEV NECAHTPCQN GGQCEDRIGS
YLCHCLHGWT GPHCEERLTT CSDSPCQNSA VCVNVTDVGF ICDCPKGFAG RTCELSEEDC
ASLHCASRTD CPDRPEDPGC QLCSRCEGIL LKRPPVTDRV LTTVAVAAVL TRQPCSKLNC
KNGGTCYLNM CHCPDGFSGS QCEVVDDPCR AGPCLFGGSC LPNQTVTQGY VCECQPGFEG
VHCERNTYDC MHDACGAHGI CIDGINGYNC DCLYGTMGKH CVSIEMPEPS IPSADANIDN
EILIDTAQRL ISGDVENVTG CSYSPCKNHA KCATAADGDS IPVRRNLTRA YTCQCSTAIG
LFEGEHCELD VDECAPSKEP GLCLNGAQCV NTYGSYYCRC PSGFYGRHCE HMIDPCTYNR
HPVCQNGGQC VSHGMTTRCN CPVGFAGPMC EVSC
//
