ID A0A074ZIF9_9TREM Unreviewed; 891 AA.
AC A0A074ZIF9;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=T265_06049 {ECO:0000313|EMBL:KER26766.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER26766.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER26766.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL596739; KER26766.1; -; Genomic_DNA.
DR RefSeq; XP_009169483.1; XM_009171219.1.
DR AlphaFoldDB; A0A074ZIF9; -.
DR STRING; 6198.A0A074ZIF9; -.
DR GeneID; 20320231; -.
DR KEGG; ovi:T265_06049; -.
DR CTD; 20320231; -.
DR OrthoDB; 2915239at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR PANTHER; PTHR14963:SF7; RHO GTPASE-ACTIVATING PROTEIN 19; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT DOMAIN 156..404
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 542..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 891 AA; 98994 MW; 5101D86E2E5791DC CRC64;
MTTSLTDPDD TCIETKTPKP NQGKPEDLED SLNQYANWLA DAVAETPEFR QFCELWPGRF
VELCKFHLSL LIDLPLEIWD DSSNTFCGTN VVGSKKLFPD LVSREPMVSR LITNGNSRGT
PWARLRGRTP NVERAETDNI GYAIHRPNRV QHGASGGLNN NKTCANEAIV QNLLSLMDVL
DNKENLANEG IFRKTGNMQR QRCVRRRIMT EKQLDIQSLM YYVEPKPWKP AGVGFGNRRW
IQSHLTPSNP ATAPPSPMVG VHDLAAALKG VLYDLPEPLL TDRLLPLFVQ VASLTSGRLD
DRGRRITLRP IEEKIACAKQ LKAVRLLCRL LPDTHQVLFK RLLVLLEHTL QHASSNRMTA
ESLGLLFGPV LFSPSKVPTR DLHTQYTNLA RLATMMITQG VNGLWYIPKS FLQDVERNRL
LYIELSLPPI ADSSLSSSSL PFLQNDYTTS ILERANSNDS GLGLTDGSQP SSDMDSAVVP
PLRVDELPAL VTCVNFTVRH SSDKDHVTNG ETEYAVAELC AAVQSLPNND PRKRRLVNRF
NATNGGLLPP TSGAGMPKHA TPHSSLYRQI PRLNRDWSAS LGDVSSGRFI RAHAGNSAFK
AAKTIRSSLR RRLALRSNVS VTGCFNSPRN LPKPLIECRS EMDFEYSQSH TSKPGSHAHV
TDQILDSGHQ LSPIFDTNCR PDVFGSCESL NLLPAPPETI MAANTRCSIM STTSISSVGA
GDLLFCCPLV EAIASPFRKL TTPSSQGRTP DSIHSGVTPL ARVFRGGFKR LRGRSPRVGL
PRSEVISIIR PLRCDDETPV DNYYPIEFDE PLEAKLKNSE ALDEQIPVER ISARSRRGPI
RQKTITSFGY RTVAHISSQS PMDRSIGHHL RRSQTMPSIP WLFTSDKKTD F
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