ID   A0A074ZJ94_9TREM        Unreviewed;       562 AA.
AC   A0A074ZJ94;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=GPI-anchor transamidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=T265_06761 {ECO:0000313|EMBL:KER25842.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER25842.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER25842.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC       biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
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DR   EMBL; KL596764; KER25842.1; -; Genomic_DNA.
DR   RefSeq; XP_009170378.1; XM_009172114.1.
DR   AlphaFoldDB; A0A074ZJ94; -.
DR   STRING; 6198.A0A074ZJ94; -.
DR   GeneID; 20320940; -.
DR   KEGG; ovi:T265_06761; -.
DR   CTD; 20320940; -.
DR   OrthoDB; 1122658at2759; -.
DR   UniPathway; UPA00196; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR   GO; GO:0003923; F:GPI-anchor transamidase activity; IEA:InterPro.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR028361; GPI_transamidase.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR48067; GPI-ANCHOR TRANSAMIDASE; 1.
DR   PANTHER; PTHR48067:SF1; GPI-ANCHOR TRANSAMIDASE; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PIRSF; PIRSF500138; GPI8; 1.
DR   PIRSF; PIRSF019663; Legumain; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   3: Inferred from homology;
KW   GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT   ACT_SITE        230
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        272
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   562 AA;  64025 MW;  24BDB00B18616940 CRC64;
     MKEMTKRLGA VGATRLPGWG PRDPHCAWLE TLQDMVANRC QWRSCCQFLS RLPELSTKSW
     LYGSEASVLN TDVTLSMVMM MMIPEARLLF ITTHARHTSN WAVLVDTSRF WFNYRHLSNT
     LAIYRHIKRL GIPDSRIILM LSDDASCSPR NPRPAQIFNN PYNPINLYGE SIEVDYRGYE
     VTVENFIRVL TGRLPPSTPT SKRLNTDEHS NILIYMTGTS FVALQLFSGH GGDGFLKFQD
     ENELSSNEMA DVVEQMWQKK RYHEILFIVD TCQAESMGKL IYSPNVVTVG SSAIGEDSLS
     LHVDKDIGVF MSDRYSYHAS EFLKGITPES KQTMDQFLSI CPKHQCLSTV VTRTELLRRP
     IRTVPVTDFF ASVRHIEAGP HVPEPTPDQL NATRALPKQQ PIRAAELRRF QVFENRCLRT
     IDRVGWHQRP RSGTIGKRDF GCGTGTSIGE CVQHEKLHWL GHVLRIPHHR LPKRVPFFIP
     NSERRPALDL DGDRVIPTAP GWRRCKVWLR TNVSGVLVVS FYPGCLNECL EVKAPRNDCS
     RLALSPFPSF IFSLTIRLSN IL
//