ID A0A074ZJN7_9TREM Unreviewed; 954 AA.
AC A0A074ZJN7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
GN ORFNames=T265_05725 {ECO:0000313|EMBL:KER27191.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER27191.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER27191.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR EMBL; KL596729; KER27191.1; -; Genomic_DNA.
DR RefSeq; XP_009169062.1; XM_009170798.1.
DR AlphaFoldDB; A0A074ZJN7; -.
DR STRING; 6198.A0A074ZJN7; -.
DR GeneID; 20319907; -.
DR KEGG; ovi:T265_05725; -.
DR CTD; 20319907; -.
DR OrthoDB; 1334466at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20188; T-box_TBX2_3-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF198; OPTOMOTOR-BLIND PROTEIN; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 363..541
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 23..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 912..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 954 AA; 104210 MW; 372B0E31CD71CBE8 CRC64;
MTFNLPLPPN TVHQLLNRSN PLLLNSPNST GTNHVSQLAA SSGSLPSSIG RTATSPSDPE
QMLFYGRHVM GQGIGAGSTG VNTAPKSSRF PHLPPPPASL HSIWDRHVFP KLMSSNLSNG
GNSVETDASN EVLSRALKTL SDLAPSSELT ASIKDYQADY LAHLNNNNGR TNSSPSISQS
RGALDGGNPL STYSSLLAGS LHKILDSKSA FKTHVRTPSR SFSHPAADVK SPDQSSTTAL
AAMAAALAVS GLKLPAHLGA ATYGPNDNTC PPASRDSGAG LSDVISPPAS YRASPVNRSD
LMATTPSLVS MISSPMDEFS RLPDFKQASS SFLMMPRLQL PLADQDVDSA DVTIDINRPK
VELVDKVLWD KFHSQGTEMV ITKSGRRMFP PFKVKVSNLD KRAKYIVLMD IVPMDDCRYK
FHNNLWMIAG KADPEMPKRM YLHPDSPSNG EQWMQKVISF HKLKLTNNIS DKHGYTILNS
MHKYQPRFHL VRANDILRLS TSRFHTYTFK ETQFLAVTAY QNEKITQLKI DHNPFAKGFR
ESGGGRREKN KRSENLKTGP LRLSHSGTET RRDSAADLFD GSNLTSSDTE NEPDMEEMLA
DGVEERSSRN GTQSMVVDYA EQHRFHKDSK QSVKRFAPKR NISGASVNVR LDSPSKLQFP
SFPGSIKGSN VSHTTKRTQS FTPDVLPQIV GRRTNGSSPP NVTILSRGLY LPDGRKELAD
SGVEDVGPAA KYLCRLKDDN GTGVPTFPYR PTSSHSSISN CYSTPWSDPL SPTSSKVENP
PEPLEAQCNF PQFTHHAEME PNESTRIPPN MDVLMRSPQY LSLLGNYIYQ NPQFIPQFLS
LLYHQNFAQS LGISKEESPT NLSVGGRLSS WSNSNPGETN IPTGNMNVTS ASAGIQSSSV
ASFSISALTN SPITSKKSCT DSSPSAELNN EESSESNDEK PMEDVDDNAH VTIE
//
