ID A0A074ZSZ5_9TREM Unreviewed; 426 AA.
AC A0A074ZSZ5;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=26S proteasome regulatory subunit 8 {ECO:0000256|ARBA:ARBA00040909};
DE Flags: Fragment;
GN ORFNames=T265_13205 {ECO:0000313|EMBL:KER30216.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER30216.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER30216.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; KL596664; KER30216.1; -; Genomic_DNA.
DR RefSeq; XP_009166026.1; XM_009167762.1.
DR AlphaFoldDB; A0A074ZSZ5; -.
DR STRING; 6198.A0A074ZSZ5; -.
DR GeneID; 20327372; -.
DR KEGG; ovi:T265_13205; -.
DR CTD; 20327372; -.
DR OrthoDB; 360215at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF166; 26S PROTEASOME REGULATORY SUBUNIT 8; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT DOMAIN 202..341
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 55..89
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KER30216.1"
SQ SEQUENCE 426 AA; 48123 MW; A8C8B3EBDC81F542 CRC64;
DVETLPTRSP KYKAGDPSRK YKRELEKEVA ELPAATTDGI KNYYMNKIDE HQFIVTEKLQ
NLRRLEAQRN ELNAKVRMLR EELQLLQELG SYVGEVVKAM DKKKVLVKVQ PEGKFVVDID
KNIDISQISP NCRVALRNES YTLHKILPSK IDPLVSLMMV EKVPDSTYEM IGGLDKQIKE
IKEVIELPVK HPELFEALGI AQPKGVLLYG PPGTGKTLLA RAVAHHTECT FIRVSGSELV
QKFIGEGARM VRELFVMARE HAPSIIFMDE VDSIGSTRVE SSSGGDSEVQ RTMLELLNQL
DGFEPKQNIK VIMATNRIDI LDSALLRPGR IDRKIEFPAP NEEARLDILK IHSRKMNLTR
DIDLRKLAES MPGASGAEVK GVCTEAGMYA LRERRVHVTQ EDFELAVAKV MQKDSDKNVS
IKKLWK
//
