ID A0A074ZUE0_9TREM Unreviewed; 481 AA.
AC A0A074ZUE0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Ionotropic glutamate receptor C-terminal domain-containing protein {ECO:0000259|Pfam:PF00060};
GN ORFNames=T265_02868 {ECO:0000313|EMBL:KER30716.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER30716.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER30716.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL596656; KER30716.1; -; Genomic_DNA.
DR RefSeq; XP_009165485.1; XM_009167221.1.
DR AlphaFoldDB; A0A074ZUE0; -.
DR STRING; 6198.A0A074ZUE0; -.
DR GeneID; 20317056; -.
DR KEGG; ovi:T265_02868; -.
DR CTD; 20317056; -.
DR OrthoDB; 5594882at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR Pfam; PF00060; Lig_chan; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..481
FT /note="Ionotropic glutamate receptor C-terminal domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001705522"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 176..456
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 481 AA; 54297 MW; B5D2C7338EF46A60 CRC64;
MHLRAARLHL ICTLVQLIGL PGLIHGRSWR VGVPAGFPFT DPDTENTEPS GIIYDLFENA
ESLSAVDNFS LVPMSNWFEP VQLDQTWNMT ALESGSLGCI AKLNTPNGSD LCLFVQSRAT
LEALELMPEA SNLTITSVPW MSLRPVLLAA CTGSACPWKI EPSILGAMYF MRPFHSSVWS
LLLLYSLTTA GLLFVFEMTH TYRFGKKVVQ PAPDENRFTL YESFMCVALA MFLQPFHKHP
KSWAGMILTV FWYAFCLICI ITYALGVSRL LFQTEEQVES HNSLTISVEK ELACERHSFW
CNLLHDQMHM PITEVDLPRD ESGYIVLSSL DWQKPLLVDQ LTARLIVYQT IKVNESGSNM
YVHWLPAHFD CPGGTQQPPF PSLYLNFAAA WPTVIRSVNY YIRIQQESAA LYRLANKWNL
DFVEDTKLCR PTEAAKQAAP VRMYQMNGPL LFMIIGALSS LVGQFCQLFY YSVIKKVGSA
V
//
