ID   A0A074ZWQ0_9TREM        Unreviewed;       715 AA.
AC   A0A074ZWQ0;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=ACB domain-containing protein {ECO:0000259|Pfam:PF00887};
GN   ORFNames=T265_05254 {ECO:0000313|EMBL:KER27765.1};
OS   Opisthorchis viverrini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX   NCBI_TaxID=6198 {ECO:0000313|EMBL:KER27765.1, ECO:0000313|Proteomes:UP000054324};
RN   [1] {ECO:0000313|EMBL:KER27765.1, ECO:0000313|Proteomes:UP000054324}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA   Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA   Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA   Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT   "Opisthorchis viverrini - life in the bile duct.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KL596715; KER27765.1; -; Genomic_DNA.
DR   RefSeq; XP_009168487.1; XM_009170223.1.
DR   AlphaFoldDB; A0A074ZWQ0; -.
DR   STRING; 6198.A0A074ZWQ0; -.
DR   GeneID; 20319436; -.
DR   KEGG; ovi:T265_05254; -.
DR   CTD; 20319436; -.
DR   OrthoDB; 553487at2759; -.
DR   Proteomes; UP000054324; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProt.
DR   GO; GO:0004165; F:delta(3)-delta(2)-enoyl-CoA isomerase activity; IEA:UniProt.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR   InterPro; IPR000582; Acyl-CoA-binding_protein.
DR   InterPro; IPR035984; Acyl-CoA-binding_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR037272; SNS_sf.
DR   PANTHER; PTHR43684; -; 1.
DR   PANTHER; PTHR43684:SF1; ENOYL-COA DELTA ISOMERASE 2; 1.
DR   Pfam; PF00887; ACBP; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   Pfam; PF00209; SNF; 3.
DR   SUPFAM; SSF47027; Acyl-CoA binding protein; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
DR   SUPFAM; SSF161070; SNF-like; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054324};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        70..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          216..249
FT                   /note="ACB"
FT                   /evidence="ECO:0000259|Pfam:PF00887"
SQ   SEQUENCE   715 AA;  79685 MW;  E23CE51F3D426F47 CRC64;
     MSEGIALNSS PVNAMEQSEN KYPREQSLEA NEGVEHELWS NQCDFFLSIL GYAIDLANVW
     RFPYICFTNG GGACAFLIPY FILMVCTALP AFYLELILGQ RHRHGAIALW DICPVFRDLT
     AILFININDL QVVYVTALCP YLLLAVLLIN GAMLKGAREG IWYFVRPQFH RLGELKVRPG
     LVFQIYPFAI GTLPVAPFWA FTFFLLLIML GIDSGATLGD CTDDKPGALN FVQKAKWQAW
     SALKSMSKRA DASLLDWIPV DSRLCAVRLA TSVKESHKRE VDRCLSIMPA YAPTDSSSDA
     IRGSFYDVLN TLLRRAKSSD VVVAGDSNSQ ALSSTGYQTE RSHCLNLGKL SQPEHNLMRR
     IIRRQVKRIV QADRELRWTQ KAKETEEAQK AGNIRSLFQL ARATGPWKHT SPSSSIFHFS
     VSSILQEEAA SKYISIISEL VDKEKPNVEP TTTHQAQAPG LESTVSENGI LQICLNRPEK
     KNAITREMYE RWTELLNDAA VNPDIKVVAV TGKGDYFSSG NDLRATVKPI QEGHSVVEVA
     RAGRDLLNRF VNAYINFPKP LVGLVNGPAI GISVSTLGLY DYVLASDNAT FQTPFVSTGQ
     TPEGCSSYTF PRLMGPMIAN DMLLFGRKLS ATEACSYGLV TRVVPQSRFS EECSKFLNSV
     VEMPAQTLLL SKEAIRIRDR ETLVSVNALE CDRLMERWTS PEFIQAVTAF LQRKK
//