ID A0A075AQL4_ROZAC Unreviewed; 898 AA.
AC A0A075AQL4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Exportin-T {ECO:0000256|ARBA:ARBA00018928, ECO:0000256|RuleBase:RU366037};
DE AltName: Full=Exportin(tRNA) {ECO:0000256|RuleBase:RU366037};
DE AltName: Full=tRNA exportin {ECO:0000256|RuleBase:RU366037};
GN ORFNames=O9G_005049 {ECO:0000313|EMBL:EPZ30882.1}, ROZALSC1DRAFT_30840
GN {ECO:0000313|EMBL:RKP17340.1};
OS Rozella allomycis (strain CSF55).
OC Eukaryota; Fungi; Fungi incertae sedis; Cryptomycota;
OC Cryptomycota incertae sedis; Rozella.
OX NCBI_TaxID=988480 {ECO:0000313|EMBL:EPZ30882.1, ECO:0000313|Proteomes:UP000030755};
RN [1] {ECO:0000313|EMBL:EPZ30882.1, ECO:0000313|Proteomes:UP000030755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|EMBL:EPZ30882.1}, and CSF55
RC {ECO:0000313|EMBL:EPZ30882.1, ECO:0000313|Proteomes:UP000030755};
RX PubMed=23932404; DOI=10.1016/j.cub.2013.06.057;
RA James T.Y., Pelin A., Bonen L., Ahrendt S., Sain D., Corradi N.,
RA Stajich J.E.;
RT "Shared signatures of parasitism and phylogenomics unite Cryptomycota and
RT microsporidia.";
RL Curr. Biol. 23:1548-1553(2013).
RN [2] {ECO:0000313|Proteomes:UP000281549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|Proteomes:UP000281549};
RX PubMed=30297742; DOI=10.1038/s41564-018-0261-0;
RA Ahrendt S.R., Quandt C.A., Ciobanu D., Clum A., Salamov A.,
RA Andreopoulos B., Cheng J.F., Woyke T., Pelin A., Henrissat B.,
RA Reynolds N.K., Benny G.L., Smith M.E., James T.Y., Grigoriev I.V.;
RT "Leveraging single-cell genomics to expand the fungal tree of life.";
RL Nat. Microbiol. 3:1417-1428(2018).
RN [3] {ECO:0000313|EMBL:RKP17340.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CSF55 {ECO:0000313|EMBL:RKP17340.1};
RG DOE Joint Genome Institute;
RA Ahrendt S.R., Quandt C.A., Ciobanu D., Clum A., Salamov A.,
RA Andreopoulos B., Cheng J.-F., Woyke T., Pelin A., Henrissat B.,
RA Reynolds N., Benny G.L., Smith M.E., James T.Y., Grigoriev I.V.;
RT "Leveraging single-cell genomics to expand the Fungal Tree of Life.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex.
CC {ECO:0000256|RuleBase:RU366037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU366037}. Nucleus
CC {ECO:0000256|RuleBase:RU366037}. Note=Shuttles between the nucleus and
CC the cytoplasm. {ECO:0000256|RuleBase:RU366037}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466, ECO:0000256|RuleBase:RU366037}.
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DR EMBL; KE561362; EPZ30882.1; -; Genomic_DNA.
DR EMBL; ML005892; RKP17340.1; -; Genomic_DNA.
DR STRING; 988480.A0A075AQL4; -.
DR EnsemblFungi; EPZ30882; EPZ30882; O9G_005049.
DR HOGENOM; CLU_004414_0_1_1; -.
DR OMA; CALIDCH; -.
DR OrthoDB; 2546268at2759; -.
DR Proteomes; UP000030755; Unassembled WGS sequence.
DR Proteomes; UP000281549; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071528; P:tRNA re-export from nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045546; Exportin-T_C.
DR InterPro; IPR040017; XPOT.
DR PANTHER; PTHR15952:SF11; EXPORTIN-T; 1.
DR PANTHER; PTHR15952; EXPORTIN-T/LOS1; 1.
DR Pfam; PF19282; Exportin-T; 2.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU366037};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366037};
KW Reference proteome {ECO:0000313|Proteomes:UP000030755};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU366037};
KW Transport {ECO:0000256|RuleBase:RU366037};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555,
KW ECO:0000256|RuleBase:RU366037}.
FT DOMAIN 92..243
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 304..536
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
FT DOMAIN 548..890
FT /note="Exportin-T C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19282"
SQ SEQUENCE 898 AA; 103455 MW; 8387FD0AB1A67C07 CRC64;
METLEQAVLC SLNAVPASAE IRQQAYDYCE DVKKSPEGWK LGLELFLRQP RTFFCLQLLE
HAIKYKVVCG SELSGLRGEM MGEIGGWDEL DVKNKLVQVV GLMFEGEYLT SWPNFFKDMI
YLVQSANQTH VYEFYLRLCL SIDEEVVTTA GGRAEEAEAH QRHTMLKDQM RVNDMRDLVE
SWIGIMMSHF VSGRKEIVNL CVRLLGRYSY WADINLILNE RVLRELMVYM DDMELQESVI
ECISMIEEDK FAVIEMINIP MMLSKIKGWE DVDEAIKIAK FINIVGSEMC GLSVIGSLKV
FYACQSLFPF AMRAFSHEYD DVVCEILPFI SSFLYVLKKI KKENGVVPEQ LISNVETMFK
ITIVKMKREM EEASEEEFAM FQEFRKSLRV IFDGLISVEE EECFMILESF IQNCKGGWNE
GEVVFYTLLI YTERKNLEGL KNDSRLINIL TFVLSIQISN QFVFIPYFDL INRITTIGFF
ELKPDCIQIV LERFFIEGIM NPHPFVSERA IYLFHRFIKH LKSKLILFVD EIIRGLLPIV
HANRTVSNYL LESLGILVSL KPSQEQVNLM NLIFNPFQNQ ISSLISSNDQ QEKISTLISY
YGDFSKNVGT VKDNQVLNLI TNWIQLLIAT LNSLVESESI RKSTLKSFQK ITLAINEAAI
PFIPTILKPI LIHCSIQELS DIFPIVSLFL NKYKNTLIDI INEFLPFLNS KAFSFMATPI
EGTDDLFNLR TLRRNFLSFQ IALISFDFHI LLHNQFNQTL SSTLTICQDN QDPISQKQAF
TFLLKVVTLL DSVSGVDDFI INQITPLIYS VPLQNSFNFD DASSMAVLLQ ISILQKCILE
KKGDNYAQYL LNNFFSFNFG LDYNISLEYI QAMKALDAKG FSKVFHNFIK VLKSRNTQ
//
