ID A0A075AY19_ROZAC Unreviewed; 2446 AA.
AC A0A075AY19;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Dynein heavy chain, coiled coil stalk domain-containing protein {ECO:0000313|EMBL:EPZ35039.1};
DE Flags: Fragment;
GN ORFNames=O9G_003225 {ECO:0000313|EMBL:EPZ35039.1};
OS Rozella allomycis (strain CSF55).
OC Eukaryota; Fungi; Fungi incertae sedis; Cryptomycota;
OC Cryptomycota incertae sedis; Rozella.
OX NCBI_TaxID=988480 {ECO:0000313|EMBL:EPZ35039.1, ECO:0000313|Proteomes:UP000030755};
RN [1] {ECO:0000313|EMBL:EPZ35039.1, ECO:0000313|Proteomes:UP000030755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|EMBL:EPZ35039.1,
RC ECO:0000313|Proteomes:UP000030755};
RX PubMed=23932404; DOI=10.1016/j.cub.2013.06.057;
RA James T.Y., Pelin A., Bonen L., Ahrendt S., Sain D., Corradi N.,
RA Stajich J.E.;
RT "Shared signatures of parasitism and phylogenomics unite Cryptomycota and
RT microsporidia.";
RL Curr. Biol. 23:1548-1553(2013).
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DR EMBL; KE560897; EPZ35039.1; -; Genomic_DNA.
DR STRING; 988480.A0A075AY19; -.
DR EnsemblFungi; EPZ35039; EPZ35039; O9G_003225.
DR HOGENOM; CLU_000038_3_1_1; -.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000030755; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961:SF8; DYNEIN AXONEMAL HEAVY CHAIN 3; 1.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030755}.
FT DOMAIN 4..71
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 238..361
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 590..669
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 736..991
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 1005..1350
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 1379..1600
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 1846..1960
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 1995..2135
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 2143..2442
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 1232..1304
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPZ35039.1"
SQ SEQUENCE 2446 AA; 278395 MW; AD2F14EC1A9A3EC6 CRC64;
LISKGIISDL FPGTELPKAD HGNLIKSITE SCEKLNLQPV PVFIDKVLQV YEMMLVRHGF
MLVGEPFSGK TACYKVLQKA LTEMNEKVQV SVINPKSITM GQLYGQFDQI THEWSDGVLA
VIFRTFSSST SPDRKWIVFD GPVDAIWIEN MNTVLDDNKK LCLTSGEIIQ LSSTMSMMFE
VKDLEAASPA TVSRCGMIYM QPSSLGWKPL FVSWLRKCEL NAGANQSLRW INGGYVPLFE
LVDECLGFVR GNCGEMCQTQ DSNLVVSLMN MIESFYISND INSNTFSSNN SNANSANSNP
MSMVFLFCLV WSLGGCLNEE GRTKFDAFLK QSIIPKLELK SAVPGNVYDY CLKDGEWVHW
NSTINKTVIP LNAKYEEILV ETADTAKYSY LLKMLVVNMK AVLFVGSTGT GKSAYIKDVL
SKKLSAEKFN QIFITFSATT TCNQTQEMIE SKIEKRRKGV FGPPIGKKCL IFVDDLSMPL
KEQYGAQPPI ELLRQWMDHG GWYNLNEKNM QEFVDIQFIT AMVATTAKNV VTPRYLGHFN
AIGLTNFDDQ TLDRIFKTII DWHFSKQFSA EIVSLGGRVV EATRRVYRES MKNLLPTPAK
SHYTFNLRDF ARVVKGILTS CSKSIASKDQ LVRLWTHEVY RVFYDRLVDD SDRQWFFTLI
RDVVNSSFNN SFESCMEQYK SESEIVESDL RKLMFCDFVP GEENQKYYRE IVRFDELAAL
IEKYLVDHNA LSKKPMDLVM FRFAIEHLLR ISRVLQQPRG HMLLVGVGGS GRQSLTRLAA
YIKNIDLFQV EISKNFGYAD WQDFLRGLLK KAGGEDKQVV FLFSDNQIKN ETFLQDINNL
LNSGQVPNLL TAEDKQNITE LIKSNNPSVQ GPNAVMKCFT DRCCENLHIV LCMSPIGDVF
RVRLRQYPSI INCCTIAWYQ TWPEDALKIV ANKFLSVMDF KDIPIDNISF MCMYFHNSVI
SLSKKYYSEL KRRNYVTPTS YLELLKTFKS LLKQKQEEIS TYRFRYVNGL EKLKFASLSV
AKMQKELEAL QPELIKTKEE TDVIMKQIEK ESHEVQQVRV VVQKDEAVAS EQAASSTRMK
EECEHDLAEA LPALEAALAA LDTLKAQDIT LLKSMKSPPG NVKLVMEAVC IMKDVKSVKI
PDPNSPGKKI DDYWGPAKTM MSDMKFLDSL RTYDRDNIQP AIMKQIRQKY MDNPEFDPEK
VKNASSAAEG LCRWVRAMEC YDRVAKVVAP KKEALAIAEK ELAETMQKLT EKRLQLKSVE
ERMTKLELKF EEMTKKKESL ELQVDNCSKQ LVRAEKLINS LGDEKERWTR VAEELDIVYE
TLLGDVLIAS GSVAYLGAFT KSFRDECLND WIKICKEKKI PSSSAIKIAN TLGEPVNIRK
WIINGLPNDS FSIDNAVISS NTARWPLMID PQGQANRWIK NMEKSRGLQV IKLSDADYMR
TLENAIQFGT PVLLENVGEE LDPVLEPLLL KQTFKQGGQL FIRIGDSVIE FSHDFRFYIT
TKLRNPHYLP EISTKVTIIN FMITKEGLED QLLGITIAKE RPELEEMKNQ LIVQSADNKR
QLKEIEDKIL EILSSSQGNI LEDETAIQIL SSSKVLANQV KEKQATAEAT EKEIDEIRLG
YTSIATHSSI LFFCISDLAN IEPMYQYSLP WFINLFISSI ENSEKSSNVS DRLLNLKNHF
TKSLYNNVCR SLFEKDKLVF SLLLCSSILK SHDKINEEEW RFLLTGGLSI EKEIPPNPDK
SWISEKTWAE LNRLINLPAF NSFLADFTLN LNDWKHFNDH ADPHELPLPG KWDSELSLFQ
KLIVLRCFRS DKLVPGVKKF VKESLGNEFV EPPPFELSSC YSDSSPTTPL IFVLSPGADP
MTGLLKFAES KGFDDKKISS ISLGQGQGVI ASRIITRAIS EGSWVILQNC HLAVSWLPSL
EQIVEELSPD QTNPNFRLWL TSYPSEKFPV SILQNGVKMT TEPPKGLKAN LYRSFTGDPI
SEPSFFNGCN KQVAFEKLLF GLCFFHAVIQ ERRQYGPIGW NIPYEFNDTD LRISARQVRI
FLNSYDEIPF DALRYLTGEC NYGGRVTDDK DRRTLMSLLN IFYTPKIMDD DYKFSNSGIY
FAPRPTNSSF DSYLEFIKNL PMDSKPEVFH LNDNADITKN QLETFNLLSA VLLTQNSTES
RGGQSNEQLI IDLASDLLNR LPNDFNMVDI TTKYPVNYND SMNTVLIQEC IRFQALLDLI
RSSLNSLLKA LKGLVLMTPQ LETTAQSMLI AKIPPLWLSK SYPSIKPLGS YFSDFLNRIS
FFQSWYDNGP PPVFWISGFF FTQSFLTGCL QNYARKFSLP IDILALDFEI LDGSTNTKVP
PVDGVYVHGL YLEGARWNSE THMLAESLPK VLFDQLPVLW FKPMDRAKIA QRNAYDCPVY
KTATRRGTLS TTGHSTNYVL SIRLPTDLQE SHWINRGVAA LCSLSD
//
