ID A0A075AZ48_ROZAC Unreviewed; 584 AA.
AC A0A075AZ48;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=SAM-dependent MTase RsmB/NOP-type domain-containing protein {ECO:0000259|PROSITE:PS51686};
GN ORFNames=O9G_005213 {ECO:0000313|EMBL:EPZ33839.1};
OS Rozella allomycis (strain CSF55).
OC Eukaryota; Fungi; Fungi incertae sedis; Cryptomycota;
OC Cryptomycota incertae sedis; Rozella.
OX NCBI_TaxID=988480 {ECO:0000313|EMBL:EPZ33839.1, ECO:0000313|Proteomes:UP000030755};
RN [1] {ECO:0000313|EMBL:EPZ33839.1, ECO:0000313|Proteomes:UP000030755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|EMBL:EPZ33839.1,
RC ECO:0000313|Proteomes:UP000030755};
RX PubMed=23932404; DOI=10.1016/j.cub.2013.06.057;
RA James T.Y., Pelin A., Bonen L., Ahrendt S., Sain D., Corradi N.,
RA Stajich J.E.;
RT "Shared signatures of parasitism and phylogenomics unite Cryptomycota and
RT microsporidia.";
RL Curr. Biol. 23:1548-1553(2013).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE561033; EPZ33839.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A075AZ48; -.
DR STRING; 988480.A0A075AZ48; -.
DR EnsemblFungi; EPZ33839; EPZ33839; O9G_005213.
DR HOGENOM; CLU_467040_0_0_1; -.
DR OrthoDB; 1331370at2759; -.
DR Proteomes; UP000030755; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR042620; NSUN7.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14663:SF2; METHYLTRANSFERASE NSUN7-RELATED; 1.
DR PANTHER; PTHR14663; UNCHARACTERIZED; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000030755};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 152..458
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT BINDING 289
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 313
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 584 AA; 67456 MW; AE2AB349B21B55A8 CRC64;
MDDISTNYLR SKLAFSEPSI FEKEIKAVPY SDLDYVMAAE LLDTFVGTIS KRTNPVKNVT
NENRHKVNKR SKTQFLVNYP ELLQNLSLLK VLLYQVLKNQ FNYNSGGIVY QHDSEYPQVR
EFAEAIYAYK VRLAACYARL RIEKQAIGSS PEEVLRNILP KEDRQETQIG VTKEQVLKKL
SKLGYNVVDR KVDLDKKNDN NCITFDKDFD DLLVIPPALF NEIGESELIH RGWLAIQEKP
SIVGPLEASI SVKDDEFPVI IDARAGNGRT RASTLAAMIH NKGKIFAVEE KPGRLATLKR
RLQLYNIKRN LLDPNDPHFE NVSTIICEPP SSGSSIIDKF SYVIQEEELP EGEVDSKDLE
RLKNKQIETV EHALKCKNRM LLRLVPNVQT IIYVTHSVHF EENEQVVCEI LDRNHVELDY
VMPQFLNDEV KPFEFKECFK LAPSDYGNGI FVACFRKLYD EPIVEQSGDI FESEINNEQT
MEEELIQIEH GQGNRKQKFK AKRILAQRHQ FLNNDKNLKK SYIREDIDDI LVKGKPIYNQ
VKFMKGLGII GHSLSKFYKS NVSNNEIRKR NVWKYPVPNP KPWK
//
