ID A0A075B519_ROZAC Unreviewed; 391 AA.
AC A0A075B519;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Saccharopine dehydrogenase / Homospermidine synthase domain-containing protein {ECO:0000313|EMBL:EPZ36846.1};
GN ORFNames=O9G_002129 {ECO:0000313|EMBL:EPZ36846.1}, ROZALSC1DRAFT_29965
GN {ECO:0000313|EMBL:RKP18329.1};
OS Rozella allomycis (strain CSF55).
OC Eukaryota; Fungi; Fungi incertae sedis; Cryptomycota;
OC Cryptomycota incertae sedis; Rozella.
OX NCBI_TaxID=988480 {ECO:0000313|EMBL:EPZ36846.1, ECO:0000313|Proteomes:UP000030755};
RN [1] {ECO:0000313|EMBL:EPZ36846.1, ECO:0000313|Proteomes:UP000030755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|EMBL:EPZ36846.1,
RC ECO:0000313|Proteomes:UP000030755}, and CSF55
RC {ECO:0000313|EMBL:EPZ36846.1};
RX PubMed=23932404; DOI=10.1016/j.cub.2013.06.057;
RA James T.Y., Pelin A., Bonen L., Ahrendt S., Sain D., Corradi N.,
RA Stajich J.E.;
RT "Shared signatures of parasitism and phylogenomics unite Cryptomycota and
RT microsporidia.";
RL Curr. Biol. 23:1548-1553(2013).
RN [2] {ECO:0000313|Proteomes:UP000281549}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSF55 {ECO:0000313|Proteomes:UP000281549};
RX PubMed=30297742; DOI=10.1038/s41564-018-0261-0;
RA Ahrendt S.R., Quandt C.A., Ciobanu D., Clum A., Salamov A.,
RA Andreopoulos B., Cheng J.F., Woyke T., Pelin A., Henrissat B.,
RA Reynolds N.K., Benny G.L., Smith M.E., James T.Y., Grigoriev I.V.;
RT "Leveraging single-cell genomics to expand the fungal tree of life.";
RL Nat. Microbiol. 3:1417-1428(2018).
RN [3] {ECO:0000313|EMBL:RKP18329.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CSF55 {ECO:0000313|EMBL:RKP18329.1};
RG DOE Joint Genome Institute;
RA Ahrendt S.R., Quandt C.A., Ciobanu D., Clum A., Salamov A.,
RA Andreopoulos B., Cheng J.-F., Woyke T., Pelin A., Henrissat B.,
RA Reynolds N., Benny G.L., Smith M.E., James T.Y., Grigoriev I.V.;
RT "Leveraging single-cell genomics to expand the Fungal Tree of Life.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00038048}.
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DR EMBL; KE560428; EPZ36846.1; -; Genomic_DNA.
DR EMBL; ML005492; RKP18329.1; -; Genomic_DNA.
DR EnsemblFungi; EPZ36846; EPZ36846; O9G_002129.
DR HOGENOM; CLU_031002_1_0_1; -.
DR OMA; KRPVQMH; -.
DR OrthoDB; 5479972at2759; -.
DR Proteomes; UP000030755; Unassembled WGS sequence.
DR Proteomes; UP000281549; Unassembled WGS sequence.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030755}.
FT DOMAIN 9..133
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
SQ SEQUENCE 391 AA; 44389 MW; 798DC908F55EE04C CRC64;
MERERKFDIV IFGASGFTGR YVIEYALKHI DSTIKIAVAG RSIQKLQSIL IADVSDSASL
NSMAKSTKVV INLTGPYRTL GEPVIKACIE NFTDYVDITG EPEVNVELYW KKFMEKMHFK
YNNQAKENGV ICVQACGFDS VPADITTLKM QRKLNELIPD VDIEYIESYL SLHSDLKITA
HYTTWESAVL GFSNYKSFSS WRKKKGLNSD IVKKTSNYKP IQGWRWHNML NCYVNLFPGA
DASVVKRSQT FLADKGFIRY VPYGAYFTTE SWWSKLKFEI FGLLFLYPSF FSFGAFSHEG
PSKEQVDHTF FTMISLASVI LTNYLCTEPG YVSTSMIIIQ SAICILKDKQ KIMAHNKNKG
GIFTPSAAFY GTSFLEALEK CFDFSNVSEI N
//
