ID A0A075JJ06_9MICO Unreviewed; 760 AA.
AC A0A075JJ06;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Acetylneuraminic acid synthetase {ECO:0000313|EMBL:AIF41327.1};
GN ORFNames=HX89_10675 {ECO:0000313|EMBL:AIF41327.1};
OS Dermacoccus nishinomiyaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermacoccaceae;
OC Dermacoccus.
OX NCBI_TaxID=1274 {ECO:0000313|EMBL:AIF41327.1, ECO:0000313|Proteomes:UP000027986};
RN [1] {ECO:0000313|EMBL:AIF41327.1, ECO:0000313|Proteomes:UP000027986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M25 {ECO:0000313|EMBL:AIF41327.1,
RC ECO:0000313|Proteomes:UP000027986};
RA Hong K.W., Chan K.G.;
RT "Genome Sequencing of Dermacoccus nishinomiyaensis.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP008889; AIF41327.1; -; Genomic_DNA.
DR RefSeq; WP_038569045.1; NZ_CP008889.1.
DR AlphaFoldDB; A0A075JJ06; -.
DR GeneID; 41841573; -.
DR KEGG; dni:HX89_10675; -.
DR eggNOG; COG0517; Bacteria.
DR eggNOG; COG1082; Bacteria.
DR eggNOG; COG2089; Bacteria.
DR HOGENOM; CLU_371249_0_0_11; -.
DR OrthoDB; 9814210at2; -.
DR Proteomes; UP000027986; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR CDD; cd17773; CBS_pair_NeuB; 1.
DR CDD; cd11615; SAF_NeuB_like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 3.20.20.150; Divalent-metal-dependent TIM barrel enzymes; 1.
DR InterPro; IPR006190; AFP_Neu5c_C.
DR InterPro; IPR036732; AFP_Neu5c_C_sf.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR013132; Neu5Ac_N.
DR InterPro; IPR013974; SAF.
DR InterPro; IPR036237; Xyl_isomerase-like_sf.
DR InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR PANTHER; PTHR42966:SF3; BLR5971 PROTEIN; 1.
DR PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR Pfam; PF01261; AP_endonuc_2; 1.
DR Pfam; PF03102; NeuB; 1.
DR Pfam; PF08666; SAF; 1.
DR SMART; SM00858; SAF; 1.
DR SUPFAM; SSF51269; AFP III-like domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF51658; Xylose isomerase-like; 1.
DR PROSITE; PS50844; AFP_LIKE; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000027986}.
FT DOMAIN 1..64
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 407..465
FT /note="AFP-like"
FT /evidence="ECO:0000259|PROSITE:PS50844"
SQ SEQUENCE 760 AA; 83746 MW; 2F8B125695291739 CRC64;
MTTIAREIAP YVVFSDDTIL AALNKISDNK AGIVFCVDSH GILQGALSDG DFRRWVTAHP
SADLSTSVMA AAHTSPVKLA YGTETSTISQ AFRDGVRVIP LVDERGHVRA VARNALGSEI
RIGRHAIGEG NRCLVIAEIG NNHQGDMELA KQLVDLAKKS GADAVKFQLR DLTGLYRQGD
FASSAGEDLG AQYTMNLLAK YSFTNEQMIE ILDYCKSVDI DAFCTPWDEA SLRVLADYGV
PALKIASADM TNHDLLRACA AEHLPMLVST GMSTEDEIVA SVDVMRQAGG EFVLLQVQST
YPAPFKDINL KYMDRLAELG ECPVGYSGHE RGYHVPIAAV ARGAHVVEKH FTIDKTLEGN
DHQVSLLPEE FAEMVTKIRE VESALGNGET RAVSTGELMN RANLAKSLVA TRDIAAGAKL
TRADVTIKSP GRGLQPNRLE ALVGRTMRRP IESGDFFYAT DLTDAVAHGR AYEFKRPWGL
PVRYHDARKL LGAGETLTNP DFLEFHLSYK DVEMSMEQID AAFGSKKFDG MFHTVHCPDL
YAGDFIINLA SDDEATWERS IHEVQKVVEI TRDLGRWFDG NGEPPIVICT MGGFTMDAFD
TPAQRTVKYE RIAKALELID DTDARLTAQT LPPYPWLMGG QQHHNLFMDV DDTVWFCEQF
GRRLTFDLSH SKLAANFTKK PFSEYVEKLA PLSDHLHVVD AEGVDGEGPQ IGDGEIDWPA
TAAQLDRLAP GVPFIPEIWQ GHVNNGEGFW TALDRLEAWL
//
