ID A0A075JQ19_9BACI Unreviewed; 498 AA.
AC A0A075JQ19;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Nitrite extrusion protein {ECO:0000313|EMBL:AIF42213.1};
GN ORFNames=X953_02040 {ECO:0000313|EMBL:AIF42213.1};
OS Virgibacillus sp. SK37.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=403957 {ECO:0000313|EMBL:AIF42213.1, ECO:0000313|Proteomes:UP000027985};
RN [1] {ECO:0000313|EMBL:AIF42213.1, ECO:0000313|Proteomes:UP000027985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK37 {ECO:0000313|EMBL:AIF42213.1,
RC ECO:0000313|Proteomes:UP000027985};
RA Phrommao E., Yongsawatdigul J., Rodtong S., Steele J.L.;
RT "Complete genome sequence of Virgibacillus sp. SK37, a moderately
RT halophilic bacterium isolated from Thai fish sauce fermentation.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC Nitrate/nitrite porter (TC 2.A.1.8) family.
CC {ECO:0000256|ARBA:ARBA00008432}.
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DR EMBL; CP007161; AIF42213.1; -; Genomic_DNA.
DR RefSeq; WP_040954124.1; NZ_CP007161.1.
DR AlphaFoldDB; A0A075JQ19; -.
DR STRING; 403957.X953_02040; -.
DR KEGG; vir:X953_02040; -.
DR HOGENOM; CLU_001265_14_0_9; -.
DR OrthoDB; 9773404at2; -.
DR Proteomes; UP000027985; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd17341; MFS_NRT2_like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR044772; NO3_transporter.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23515; HIGH-AFFINITY NITRATE TRANSPORTER 2.3; 1.
DR PANTHER; PTHR23515:SF38; NITRATE TRANSPORTER NART-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Reference proteome {ECO:0000313|Proteomes:UP000027985};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..381
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 387..427
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 454..498
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
SQ SEQUENCE 498 AA; 54834 MW; 784356BE8C04DFB5 CRC64;
MFKKVQLPLQ TTNLIVGFMV WVILSSLLTF IMEDINITPQ QASWVTAVPV ILGSVLRVPM
GYLTNVFGAR KLFMISFILL LFPVYYISIA NSFMDLIIGG LFIGIGGAVF SVGVTSLPKY
YAKEKHGFVN GIYGAGNIGT AITAFAAPVI AGQIGWSLTV QLYMVLLAIF VVANFFLGDK
KEEMKVKASL IEQIKGVYRD EKLWLFSLFY FITFGSFVAF TVYLPNFLVN NFGLDSVDAG
VRTAGFIALT TFLRPLGGWL ADRFKPFVIL MYVFGIFTIA ALILSFAPSI GLYTVGTLAI
AIAGGIGNGV IFKLVPMYFN KQAGIANGIV AAMGGLGGFF PPLMLTTLYS VTGHYAIGFM
ALSQVALASL ILVIWMYFNK RLALSDEILN TTPLGMMVTN KKGKIIKINP AFTELTGYSE
EEAIGNNPNM LSSDKHTNDF YDNMWDNLNR HGFWQGEIWN KRKNGEFYLE FLTINALRDD
AGEVTQYAGV FSDITDKG
//
