ID A0A075LPB8_9BACI Unreviewed; 391 AA.
AC A0A075LPB8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:AIF67971.1};
GN ORFNames=GZ22_15925 {ECO:0000313|EMBL:AIF67971.1};
OS Terribacillus goriensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Terribacillus.
OX NCBI_TaxID=386490 {ECO:0000313|EMBL:AIF67971.1, ECO:0000313|Proteomes:UP000027980};
RN [1] {ECO:0000313|EMBL:AIF67971.1, ECO:0000313|Proteomes:UP000027980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP602 {ECO:0000313|EMBL:AIF67971.1,
RC ECO:0000313|Proteomes:UP000027980};
RA Wang Y., Lu P., Zhang L.;
RT "Complete genome sequence of a moderately halophilic bacterium
RT Terribacillus aidingensis MP602, isolated from Cryptomeria fortunei in
RT Tianmu mountain in China.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP008876; AIF67971.1; -; Genomic_DNA.
DR RefSeq; WP_038564329.1; NZ_KZ614143.1.
DR AlphaFoldDB; A0A075LPB8; -.
DR KEGG; tap:GZ22_15925; -.
DR HOGENOM; CLU_017452_2_0_9; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000027980; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF3; METAL CHAPERONE YCIC-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000027980}.
FT DOMAIN 255..370
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT COILED 144..171
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 391 AA; 44362 MW; 34015A5BBC40A091 CRC64;
MDRRIPVTVL SGYLGAGKTT LLNHLLANKQ QLKIGVLVND MSEINIDAHL VEQGGLKRTD
EKLIQLENGC ICCTLREDLI IEIDKLADLD IDYIIVESTG ISEPIPVAQS FTYQEEVLGI
DLSAKCRLDT MVTVVDSGSF WHDYQSGESL LDRQQQAVEE DEREISDLLL DQIEFADVIL
LNKADQLDKD ELQQLYSLMH TLNPEADIHQ TEFGKVEPNL VLDTKTFSFE KASQSAGWIK
ELNSEHVPET EEYGISSFVY RRQRPFHPER WMKWLEKWPS SVVRAKGFFW LASRPYTSGL
LSQAGQSLAI EAAGPWISTY SPEEQEVMRA EDEELAARWH PLYGDRMTEL VFIGIGLAKE
MIIKDLDACL LTEDEMLLDS ETFSDPLPTF A
//
