ID A0A075LPG5_9BACI Unreviewed; 386 AA.
AC A0A075LPG5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=GZ22_15265 {ECO:0000313|EMBL:AIF67862.1};
OS Terribacillus goriensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Terribacillus.
OX NCBI_TaxID=386490 {ECO:0000313|EMBL:AIF67862.1, ECO:0000313|Proteomes:UP000027980};
RN [1] {ECO:0000313|EMBL:AIF67862.1, ECO:0000313|Proteomes:UP000027980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP602 {ECO:0000313|EMBL:AIF67862.1,
RC ECO:0000313|Proteomes:UP000027980};
RA Wang Y., Lu P., Zhang L.;
RT "Complete genome sequence of a moderately halophilic bacterium
RT Terribacillus aidingensis MP602, isolated from Cryptomeria fortunei in
RT Tianmu mountain in China.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP008876; AIF67862.1; -; Genomic_DNA.
DR RefSeq; WP_038564064.1; NZ_CP008876.1.
DR AlphaFoldDB; A0A075LPG5; -.
DR KEGG; tap:GZ22_15265; -.
DR HOGENOM; CLU_041674_1_0_9; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000027980; Chromosome.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000027980}.
FT DOMAIN 30..366
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 386 AA; 43299 MW; 2C675B419D837ABA CRC64;
MALSKKRVML VFGTRPEAVK MAPLVLELKK RPEQFETIVA VTAQQREMLD QVLKIFDIKP
DYDLNIMKAR QSLAHITTKV MEGLDKLYQE IKPDIVLVHG DTTTSFAASL AAYYNQIPVG
HVEAGLRTWN KYSPFPEELN RQLTGVIADL HFSPTIQARQ NLLDENKNVE TIAVTGNSAI
DALQTTVDPN YQHPILEQAA GRRLVLVTAH RRENLGENME HMFTAIRRIA DAHPDTLIVY
PMHLNPAVRD IANRILGDHE RIQLIEPLGL IDFHNFASHA YLILTDSGGV QEEAPSLGVP
VLVLRDTTER PEGIQAGTLK LAGTDERTIF EMADKLLRDE QAHEEMSQAS NPYGDGQASI
RIADYLQYYF GLQSQPPIPF QPADPE
//
