ID A0A075NZ51_9ALTE Unreviewed; 798 AA.
AC A0A075NZ51;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=EP13_09175 {ECO:0000313|EMBL:AIF98836.1};
OS Alteromonas australica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX NCBI_TaxID=589873 {ECO:0000313|EMBL:AIF98836.1, ECO:0000313|Proteomes:UP000056090};
RN [1] {ECO:0000313|EMBL:AIF98836.1, ECO:0000313|Proteomes:UP000056090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H 17 {ECO:0000313|EMBL:AIF98836.1,
RC ECO:0000313|Proteomes:UP000056090};
RA Gonzaga A., Lopez-Perez M., Rodriguez-Valera F.;
RT "Genomes of Alteromonas australica, a world apart.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
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DR EMBL; CP008849; AIF98836.1; -; Genomic_DNA.
DR RefSeq; WP_044056990.1; NZ_CP008849.1.
DR AlphaFoldDB; A0A075NZ51; -.
DR GeneID; 78255083; -.
DR KEGG; aal:EP13_09175; -.
DR eggNOG; COG1067; Bacteria.
DR Proteomes; UP000056090; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10046:SF49; LON PROTEASE HOMOLOG-RELATED; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Reference proteome {ECO:0000313|Proteomes:UP000056090};
KW Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 566..761
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT ACT_SITE 656
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 699
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 798 AA; 88805 MW; EB860684AC6D141A CRC64;
MSGEIKHTSL TPSSLTPTIN RKAINSALKD DEALHATFIG QERAREALTF GLGINAKGYN
LYVMGEPATG RFTLVRDYIA RQVANLNAPD DWVYINNFAE EREPVALKFP TGGGKAFHKD
ISQLIDDVLD TFPVAFDNPG YQRKRANISR EFDKKYDEAI AALERYAQAN DVALYEENGE
ISFSPIVEGK PLTDTEFAAL NESQRSHFYA LIDDLENRLS ESLLSLPSWK RENSEQLRAL
DKQTAEQGIK PLLKVLEHKY SAELGILKYL KQLKTALVNA ILLIVQEERK DEKSDEFDQR
VFLEEQFLPN VLVANNVGDT APVIYEPNPT YQNLFGKIEY TNIHGGVFTN YRMIRPGALH
RANGGYLLLD VDQLIEQPYV WETLKLAVKL GRLKMDLPQQ DVGMVNAITL HPQPIDLNIK
IVLLGSRDLY YTLQDYDDEF DELFRVLVDF DLEIQVSRQA LFDFVGKVRK HLAQLNIQHV
TANAMCRLVE YSLRMAEHQQ KLSAHFSEVI ELVNEAHFFC MKSGSDTLEL HHLKTALAAK
KRRTGRVSQT LLNDIKEGHV LIATEGKAIG KVNGLTVLDI GDTAFGTPAR ITSTVFAGAS
GVVDIEREVE LGQPIHSKGV MLLTGYLGNK YAQHFPLTLS ANIALEQSYG HIDGDSASLG
ELVALISALT EIPCLQTLAI TGSINQYGEV QAVGGVNEKI EGYFDLCQHR GLTGTQGVII
PKSNAINLVL DSTVIDAVKK GLFHIYTVET VDDALSILME QEAGVLSSRS RYPKNTINYH
AVNRLYNIAL IVNGGDGE
//
