ID A0A075NZU4_9ALTE Unreviewed; 534 AA.
AC A0A075NZU4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Catalase {ECO:0000313|EMBL:AIG00155.1};
GN ORFNames=EP13_16490 {ECO:0000313|EMBL:AIG00155.1};
OS Alteromonas australica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Alteromonas/Salinimonas group; Alteromonas.
OX NCBI_TaxID=589873 {ECO:0000313|EMBL:AIG00155.1, ECO:0000313|Proteomes:UP000056090};
RN [1] {ECO:0000313|EMBL:AIG00155.1, ECO:0000313|Proteomes:UP000056090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H 17 {ECO:0000313|EMBL:AIG00155.1,
RC ECO:0000313|Proteomes:UP000056090};
RA Gonzaga A., Lopez-Perez M., Rodriguez-Valera F.;
RT "Genomes of Alteromonas australica, a world apart.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to
CC protect cells from the toxic effects of hydrogen peroxide.
CC {ECO:0000256|ARBA:ARBA00002974}.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971,
CC ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
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DR EMBL; CP008849; AIG00155.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A075NZU4; -.
DR KEGG; aal:EP13_16490; -.
DR eggNOG; COG0753; Bacteria.
DR Proteomes; UP000056090; Chromosome.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd08154; catalase_clade_1; 1.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR002226; Catalase_haem_BS.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF23; CATALASE-2; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00437; CATALASE_1; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000056090};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..534
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001707983"
FT DOMAIN 28..413
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT ACT_SITE 75
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 148
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 359
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 534 AA; 60154 MW; 0F851906434A3130 CRC64;
MKTTLSKVIL GCVTAGMLSM GVGADTLTRQ NGAPVGDNQN SQTAGPWGPV LLQDSHLIEK
LAAFDRERIP ERVVHARGVG IHGYYENYVD LSDDTVAAPF QGEGKKTEVF VRFSSVVHGH
LSPETLRDPR GFAVKFYTEQ GNWDLVGNNF PVFFIRDAIK FPDMVHAFKP SPVTNKQDAK
RIFDFFSHVP ESTHTLTMLF SDYGTPASYL NMDGSGVHAF KFVDDEGNYK YVKFTWKANQ
PIKNFTAEEA MKMQGMDFQP HTTDVYTRIG EKGETASWDL YLQELEPEQL DDFDFNPLDT
TKIWPESLVP AKKIGRLVLN RVPDNFFEET EQAAFAPSNL IPGIEPSEDR MLQGRLFSYA
DTQRYRLGVN AYRIPVNAPK NVEINNHEQH GQLRTTSTNR DVNYQPSRRL DLNEDPAYRY
SSKPLAGMTQ QIPFYKEQNF KQAGEFYRNL DKQGRKNLIN NLGGALASVP EEEIRVIISA
FMYNADKDYG KGVAKLAKAP MSKVRQAAKD LMEEQAARAA KAKKVAESLT ALMQ
//
