ID A0A075QYK8_BRELA Unreviewed; 591 AA.
AC A0A075QYK8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Oxygen-independent coproporphyrinogen-III oxidase {ECO:0000313|EMBL:AIG25442.1};
DE EC=1.3.99.22 {ECO:0000313|EMBL:AIG25442.1};
GN ORFNames=BRLA_c011020 {ECO:0000313|EMBL:AIG25442.1};
OS Brevibacillus laterosporus LMG 15441.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1042163 {ECO:0000313|EMBL:AIG25442.1, ECO:0000313|Proteomes:UP000005850};
RN [1] {ECO:0000313|EMBL:AIG25442.1, ECO:0000313|Proteomes:UP000005850}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 15441 {ECO:0000313|EMBL:AIG25442.1,
RC ECO:0000313|Proteomes:UP000005850};
RX PubMed=21914864; DOI=10.1128/JB.05696-11;
RA Djukic M., Poehlein A., Thurmer A., Daniel R.;
RT "Genome sequence of Brevibacillus laterosporus LMG 15441, a pathogen of
RT invertebrates.";
RL J. Bacteriol. 193:5535-5536(2011).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP007806; AIG25442.1; -; Genomic_DNA.
DR RefSeq; WP_003335022.1; NZ_CP007806.1.
DR AlphaFoldDB; A0A075QYK8; -.
DR STRING; 1042163.BRLA_c011020; -.
DR KEGG; blr:BRLA_c011020; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_021572_1_0_9; -.
DR Proteomes; UP000005850; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:AIG25442.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005850}.
FT DOMAIN 1..134
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 178..408
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 591 AA; 69153 MW; 9A7DE5B15FC4C6D6 CRC64;
MKILLATLNA KYIHSSLALR YLRSYAKPHY PNIELVEYTI NDVLINIVGD IHKRQPDIIA
FSCYIWNIRE TLDVINNVKK ICPNVPIILG GPEVSYDTDE WMKNYPAIDV IVMGEGEETF
LELCQAYDRA KQTGDAPLLK EVPGIAYRDG ERVRFSMQRI QTKDLNHLPS PYEEDLDELN
NRVVYFEASR GCPFRCQYCL SSIENGVRYF DLDRVKRDLK RLIDHGVKTV KFVDRTFNIN
KQYAMEIFQF LIDNHNGTIF QFEITADILK PDVVDFLAEN APPGIFRFEI GVQSTNDETN
RLVQRRQNFE KLSYTVLKIK ESGKIDQHLD LIAGLPEEDY ASFRKTFNEV FALRPEELQL
GFLKMLRGTG VRARAAEHGY IFMDQSPYEI LGNNVLSFND MQRIKRTEDI LEKYWNAHRM
DKAFEWIMAH HFATPFDFFQ EFGDYWEEQG WGRFGHQLED LFIRLQRFLE RKAPNQTSHS
LSMLKFDYLL SQKYRPRKIW WEDTINKSEL QAIYQNVASK RKDLRADFAL HAETEKEYAK
HTTVAHVSFN VEHYIKTGEM VEGNFVLVMY YPFVEGASNT FVCVPVPQTV A
//
