ID A0A075R6U2_BRELA Unreviewed; 345 AA.
AC A0A075R6U2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=O-methyltransferase {ECO:0000313|EMBL:AIG25300.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:AIG25300.1};
GN ORFNames=BRLA_c009590 {ECO:0000313|EMBL:AIG25300.1};
OS Brevibacillus laterosporus LMG 15441.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1042163 {ECO:0000313|EMBL:AIG25300.1, ECO:0000313|Proteomes:UP000005850};
RN [1] {ECO:0000313|EMBL:AIG25300.1, ECO:0000313|Proteomes:UP000005850}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 15441 {ECO:0000313|EMBL:AIG25300.1,
RC ECO:0000313|Proteomes:UP000005850};
RX PubMed=21914864; DOI=10.1128/JB.05696-11;
RA Djukic M., Poehlein A., Thurmer A., Daniel R.;
RT "Genome sequence of Brevibacillus laterosporus LMG 15441, a pathogen of
RT invertebrates.";
RL J. Bacteriol. 193:5535-5536(2011).
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DR EMBL; CP007806; AIG25300.1; -; Genomic_DNA.
DR RefSeq; WP_003335188.1; NZ_CP007806.1.
DR AlphaFoldDB; A0A075R6U2; -.
DR STRING; 1042163.BRLA_c009590; -.
DR KEGG; blr:BRLA_c009590; -.
DR eggNOG; COG2226; Bacteria.
DR HOGENOM; CLU_005533_12_0_9; -.
DR Proteomes; UP000005850; Chromosome.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.1350; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AIG25300.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005850};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:AIG25300.1}.
FT DOMAIN 122..324
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 255
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 345 AA; 39090 MW; DB60B27BA04F5FC2 CRC64;
MFLKEKDTAE MPAHVALLEK LFMPFMFQAI YVAADLHLAD HLKDGAKSIG ELAQVTQTDE
SALYRLLRSL TSMDIFKESE KGIFELTPMA EWLRSDVEGS LHSMALMLGG QPMWNLLPEL
LTSIKTGESS FEKTFKQSFY EYLNQSENKK AGDIFNLAMS HNTQRQIKQI LTNYDFSSYH
QIIDVAGNHG QLLTAILKEA SDSKGIIFDQ PYARELALAN LNKAQVSDRC EFVVGDFFKE
ITKGGDLYIL KHILHNWNDE KVLEILTQCR EAMGDSSKLL VIDSVIEEGD SKDLAKFLDL
QMLLLLGGKE RTQEEYSQLC EASGLFIHRA IKLPMSMSLL EIYPK
//
