ID A0A076G5A2_9CAUD Unreviewed; 294 AA.
AC A0A076G5A2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=DNA-directed DNA polymerase family A palm domain-containing protein {ECO:0000259|SMART:SM00482};
GN ORFNames=ICP22013AHaiti_51 {ECO:0000313|EMBL:AII27165.1};
OS Vibrio phage ICP2_2013_A_Haiti.
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Zobellviridae; Icepovirus.
OX NCBI_TaxID=1529058 {ECO:0000313|EMBL:AII27165.1, ECO:0000313|Proteomes:UP000028662};
RN [1] {ECO:0000313|Proteomes:UP000028662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=25161196; DOI=10.7554/eLife.03497;
RA Seed K.D., Yen M., Shapiro B.J., Hilaire I.J., Charles R.C., Teng J.E.,
RA Ivers L.C., Boncy J., Harris J.B., Camilli A.;
RT "Evolutionary consequences of intra-patient phage predation on microbial
RT populations.";
RL Elife 3:e03497-e03497(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KM224879; AII27165.1; -; Genomic_DNA.
DR RefSeq; YP_009056263.1; NC_024791.1.
DR GeneID; 20284071; -.
DR KEGG; vg:20284071; -.
DR OrthoDB; 308at10239; -.
DR Proteomes; UP000028662; Genome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR019760; DNA-dir_DNA_pol_A_CS.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 1.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00447; DNA_POLYMERASE_A; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000028662}.
FT DOMAIN 2..244
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
FT REGION 137..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 33425 MW; CDAF5A1E622E469B CRC64;
MSDIKRCIIS RFVGGYIMEC DFSQLEVVGG AVLTGDPMMK KDIIEGVDTH CMSASWANPK
YSYEEILAGY KAEDPFFTKL RKNAKPVNFA LQYGAGAETA ADNAGIEVEQ AQAIIDNYYK
RYCVLKQFQD DVIEQVNRSR QPSSRRTEMG MPAGRGEYRN PTGRIFTFYE YDAPDFLRKR
GQMTSFSPTQ CKNYPTQSFA TGDIVPMMLG HIYKLLMTDE TLRGKCLLIG TVHDSVVFDV
HPDVLDYAAK TIRKLMLRTP EYVERYLKVP FDMPLNCDVD IGEGAWFDMH GYKC
//
