ID A0A076HTD0_9BACT Unreviewed; 369 AA.
AC A0A076HTD0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Naringenin-chalcone synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=N008_10210 {ECO:0000313|EMBL:AII52348.1};
OS Hymenobacter sp. APR13.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1356852 {ECO:0000313|EMBL:AII52348.1, ECO:0000313|Proteomes:UP000028590};
RN [1] {ECO:0000313|EMBL:AII52348.1, ECO:0000313|Proteomes:UP000028590}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=APR13 {ECO:0000313|EMBL:AII52348.1,
RC ECO:0000313|Proteomes:UP000028590};
RA Li P., Jiang J., Kwok A.H.Y., Lou X., Xu D., Leung F.C.C.;
RT "Complete genome sequence assembly of Hymenobacter sp. APR13.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP006587; AII52348.1; -; Genomic_DNA.
DR RefSeq; WP_044015687.1; NZ_CP006587.1.
DR AlphaFoldDB; A0A076HTD0; -.
DR STRING; 1356852.N008_10210; -.
DR KEGG; hym:N008_10210; -.
DR eggNOG; COG3424; Bacteria.
DR HOGENOM; CLU_034992_0_2_10; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000028590; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028590}.
FT DOMAIN 5..215
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 235..368
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 155
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 369 AA; 40209 MW; 7098657C34164B34 CRC64;
MISYLSAIGT ANPPHRLLQA QIGDFMARAL QFDDADTRKL RALYRVSGIG HRYTVLPDYG
RANGDFTFFP NTPDLEPFPS VGARMRVYRQ EALPLAAAAA ESCLQQAPEV AADTITHLIS
VSCTGMYAPG LDIELVNRLG LRPDIQRTCV NFMGCYAAFN ALKLADAICR ANAGARVLVV
CTELCTIHFQ KHHEEDHLIS NALFGDGAAA ALVVGTPTGS RPHLAMEAFH CGLEPDGHAD
MAWHVNDFGF EMTLSSYVPK LIQRGIRKLT DDLLRNLPVQ LADIRHFAIH PGGRRILETI
EQELGLSKQD NAPAYHVLRE YGNMSSATVL FVLRELLGGF TAADAGAPIL SFAFGPGLTL
EAMLLRVVV
//
