ID A0A076MH50_AMYME Unreviewed; 415 AA.
AC A0A076MH50;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Major facilitator transporter {ECO:0000313|EMBL:AIJ20193.1};
GN ORFNames=AMETH_0101 {ECO:0000313|EMBL:AIJ20193.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ20193.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ20193.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ20193.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP009110; AIJ20193.1; -; Genomic_DNA.
DR RefSeq; WP_017986054.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MH50; -.
DR STRING; 1068978.AMETH_0101; -.
DR KEGG; amq:AMETH_0101; -.
DR PATRIC; fig|1068978.7.peg.109; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_040011_1_1_11; -.
DR OrthoDB; 7584869at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06174; MFS; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23528; -; 1.
DR PANTHER; PTHR23528:SF1; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 189..415
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 415 AA; 43069 MW; 7CAB520DF33266E6 CRC64;
MTGTRTPDAL AEPDVPVRAG WISLLFGANI GLWLGIYAPI QVLLPEQAER LDAADKELVF
GIVTGAGAVV ALLTNPLVGL ASDRTRSRFG RRHPWTLAGA LCGALGLVVL ALAPNVAIMV
VGWCLVQAGL GGMLATLTSA VPDRVPVGQR ARIGGLVGIS QMLGTVLGAV LVTVLVTSLP
GGYLACAAVV VLGAAAFVLR TRDIALPRDW RPATGFRAVL RELWVSPRRH PDFAWAWGCH
FLINLGNALG TFFLLFFLKD AVHHPDPDTG LLIMMGLYGV ALVIGGLVVG PLSDRTGRRK
PFVVGAAVVM AAAAVVLVLW QTWPAALAAS PLLGIGFGAY WAVALAILTE VLPAAQDRAK
DLGVINIANA LPQVIAPVSA TVILAELGGY PGLFAASAVA TLAAGAFILG VRSVR
//
