ID A0A076MVS2_AMYME Unreviewed; 280 AA.
AC A0A076MVS2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:AIJ23086.1};
GN Name=paaG {ECO:0000313|EMBL:AIJ23086.1};
GN ORFNames=AMETH_2994 {ECO:0000313|EMBL:AIJ23086.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ23086.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ23086.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ23086.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; CP009110; AIJ23086.1; -; Genomic_DNA.
DR RefSeq; WP_017988083.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MVS2; -.
DR STRING; 1068978.AMETH_2994; -.
DR KEGG; amq:AMETH_2994; -.
DR PATRIC; fig|1068978.7.peg.3195; -.
DR eggNOG; COG1024; Bacteria.
DR HOGENOM; CLU_009834_7_0_11; -.
DR OrthoDB; 4608673at2; -.
DR UniPathway; UPA00659; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0016853; F:isomerase activity; IEA:InterPro.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045002; Ech1-like.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR PANTHER; PTHR43149:SF1; DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43149; ENOYL-COA HYDRATASE; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 3: Inferred from homology;
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973}.
SQ SEQUENCE 280 AA; 29671 MW; E132AB4C12B100AA CRC64;
MTDTADKLPD LVSLAVERTG PVARVTLLGP GKGNAMGPDF WRELPIVFRT LDADPAVRAI
VLTGSGKNFS YGLDLPAMMG GWAPLLAGDA LAGPRTEFLR EIRVLQDSVT AVAECRTPVI
AAVSGWCIGG GVDVIAAADV RLASADAKFS VREAKVAIVA DLGSLQRLAG IIGEGHLREL
ALTGKDIDAA RAERIGLVND VYADQEAVLA AADELAREIA ANPPLVVQGV KEVLSLNTER
QVSEGLRYVS TWNAAFLPSK DIQEAVRAFM ERRAPEFTGE
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