ID A0A076MY73_AMYME Unreviewed; 724 AA.
AC A0A076MY73;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:AIJ23625.1};
GN ORFNames=AMETH_3533 {ECO:0000313|EMBL:AIJ23625.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ23625.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ23625.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ23625.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP009110; AIJ23625.1; -; Genomic_DNA.
DR RefSeq; WP_017982457.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MY73; -.
DR KEGG; amq:AMETH_3533; -.
DR PATRIC; fig|1068978.7.peg.3773; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_1_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..685
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 195..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 724 AA; 74643 MW; 67CEDF27EEB549B3 CRC64;
MFARLGRFAA DHARLVLVVA GVLLAGAAVL GMTAFGKLQS QGFDDPGSDS SRATALAEQH
FGGEDNLLFL VQARDGTVDD PATRAAGAAL TERLAADPAL ESVTSYWATG APPLRADDSR
SALIVTQPAD TSADAVKAIV DRYQGEDGLV TVTAGGGAVV GLDINDQVSR DLLVAEMIAV
PIILVLLFLV FGGVIAALLP LVVGGIAVLG TFAELSVFGS LTDVSVFAIN LTTALGLGLG
IDYALLMVSR FREELATGAD THTAVIRTVA SAGRTISFSA ATVAVALAAL LLFPQYFLRS
YAYAGIGVIV IAMLAAVVVL PALLTVLGPR VNAARLPWAR GRTPSTVSAF WGRVAAFAMK
RPALAVVPVL VVLVAAATPL LGVQFGTPDE RVLPDTASSR VVGDELRAHY PANDSRAIEV
VALGTPDAAT IAGYAGRLSE LDGAAHVSSS AGGFSQGRAD GPANPALGTP TAQKLSVVTA
ADSRSAEAET VVAEVRALPA PPGLDVAVGG DAAALVDSKD AIGSRLPVAA GLIAVTTFIL
LFLFTGSVLQ PLRALLFNLL SLSATMGMMV LVFQQGFAAG FLGFTPLPLD TSMLMLLFCI
AFGLSMDYEV FVVSRIKEAH DHGLGPREAV VHGLSRTGRI VSAAALLLAV SVFAFGTSGV
SFIQMFGIGT GLAILIDATL VRGVLLPAGM RLLGRYAWWA PEPLRRLHER IGVSESAKQP
AAAR
//
