ID A0A076MZ38_AMYME Unreviewed; 556 AA.
AC A0A076MZ38;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN Name=pgi {ECO:0000313|EMBL:AIJ24186.1};
GN ORFNames=AMETH_4094 {ECO:0000313|EMBL:AIJ24186.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ24186.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ24186.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ24186.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
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DR EMBL; CP009110; AIJ24186.1; -; Genomic_DNA.
DR RefSeq; WP_017983026.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MZ38; -.
DR STRING; 1068978.AMETH_4094; -.
DR KEGG; amq:AMETH_4094; -.
DR PATRIC; fig|1068978.7.peg.4387; -.
DR eggNOG; COG0166; Bacteria.
DR HOGENOM; CLU_036298_0_0_11; -.
DR OrthoDB; 140919at2; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 2.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973}.
SQ SEQUENCE 556 AA; 57490 MW; 523C7C98E1F54F13 CRC64;
MVGEELTVTI SDEELAAQAA PLVDELVSDQ VASKVAAQDP TLWGPDAESE ASIRLSWTTL
HKSSRPLIGE IEALREELRG EGVDRIVLAG MGGSSLAPEV IAATENVALT VLDTTDPGQV
ADALAGDLQR TVLVVSSKSG GTVETDSHRR IFAKAFADNG IDAARRIVVV TDPGSPLSEL
AEKEGYRKVF LADPHVGGRY SALTAFGLVP AGLAGADIAR LLDQAAAAAQ VLGNDSADNP
AVKLAAAWAA AHNAGAEKVV LADTGSGITG FADWAEQLIA ESTGKLGTGL LPVAVDGPAA
PGFADAGADA TPVAIGPVTG AAKVATTGSL GAQFLLWEFA TAIAGRLLKI NPFDQPDVEA
AKKAARSLLD DPSKLTGGET PTTVDDAVEI FAPRELAAAR SATVEGGGGR REGVSGDGSL
SDVLREFLAT APEGGYLAVQ AYLDRLDDAS AALLRPELAK RTGLQTTFGW GPRFLHSTGQ
YHKGGHQNGI FLQITGANED DLDVPDRPYT LGQLQHAQAL GDGQVLTERG RPVLRLHLTD
RAAGLAELMR AVQEAE
//
