ID A0A076N0X0_AMYME Unreviewed; 461 AA.
AC A0A076N0X0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Tryptophanase {ECO:0000313|EMBL:AIJ24500.1};
GN Name=tnaA {ECO:0000313|EMBL:AIJ24500.1};
GN ORFNames=AMETH_4408 {ECO:0000313|EMBL:AIJ24500.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ24500.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ24500.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ24500.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
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DR EMBL; CP009110; AIJ24500.1; -; Genomic_DNA.
DR RefSeq; WP_017983334.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076N0X0; -.
DR STRING; 1068978.AMETH_4408; -.
DR KEGG; amq:AMETH_4408; -.
DR PATRIC; fig|1068978.7.peg.4723; -.
DR eggNOG; COG3033; Bacteria.
DR HOGENOM; CLU_047223_0_0_11; -.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000062973}.
FT DOMAIN 45..422
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
SQ SEQUENCE 461 AA; 49954 MW; EF7FE84D56ED71F6 CRC64;
MKSFPPYRVQ VVKAIPITTR EEREEALARA GYNMFDLPAN MVTIDLLTDS GTGAVSAAQE
AGAAAADRSY AGSDSWFRFK SALEDLTSFP HLFPVHQGRA AERILFSTAL KPGQISLSNT
HFDTTRANVE LAGAEARDLP CPEAADLDSR DPFKGNIDLG ALEETLSGPD GSRVGQVLIT
ITNNGGGGQP VSMANLKAVR ALCDRFGVPF FLDAARFAEN SWLIIQRENG YVGKTPKEVA
QETFALADGF VASLKKDAIS PMGAAIGVRD EQLAKQCEAI LIATEGFRTY GGLGGHDLER
VAQGLQEVVD PDYLRNRAEE TAHFARLINE AGVDIVQPAG VHGLYLNAGR LLQHMPPHGF
PGHALACELY LAGGIRCAEL GSLYLGTFDD EHNLISPAPF ELVRLAIPRR TYTLAHLEYV
ADVLASIAKN PESVPEYRVT HAPQLLRHFN LKLRQVPRTV S
//
