ID   A0A076NK52_9CORY        Unreviewed;       603 AA.
AC   A0A076NK52;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:AIJ33798.1};
DE   SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:SNV75406.1};
GN   Name=pbpA_2 {ECO:0000313|EMBL:SNV75406.1};
GN   ORFNames=CIMIT_07680 {ECO:0000313|EMBL:AIJ33798.1}, SAMEA4535761_01596
GN   {ECO:0000313|EMBL:SNV75406.1};
OS   Corynebacterium imitans.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=156978 {ECO:0000313|EMBL:AIJ33798.1, ECO:0000313|Proteomes:UP000028780};
RN   [1] {ECO:0000313|EMBL:AIJ33798.1, ECO:0000313|Proteomes:UP000028780}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44264 {ECO:0000313|EMBL:AIJ33798.1,
RC   ECO:0000313|Proteomes:UP000028780};
RA   Mollmann S., Albersmeier A., Ruckert C., Tauch A.;
RT   "Complete genome sequence of Corynebacterium imitans DSM 44264, isolated
RT   from a five-month-old boy with suspected pharyngeal diphtheria.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:SNV75406.1, ECO:0000313|Proteomes:UP000215374}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC13015 {ECO:0000313|EMBL:SNV75406.1,
RC   ECO:0000313|Proteomes:UP000215374};
RG   Pathogen Informatics;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; CP009211; AIJ33798.1; -; Genomic_DNA.
DR   EMBL; LT906467; SNV75406.1; -; Genomic_DNA.
DR   RefSeq; WP_038591218.1; NZ_LT906467.1.
DR   AlphaFoldDB; A0A076NK52; -.
DR   STRING; 156978.CIMIT_07680; -.
DR   KEGG; cii:CIMIT_07680; -.
DR   eggNOG; COG0768; Bacteria.
DR   HOGENOM; CLU_025328_0_0_11; -.
DR   OrthoDB; 5241017at2; -.
DR   Proteomes; UP000028780; Chromosome.
DR   Proteomes; UP000215374; Chromosome 1.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR007887; MecA_N.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF05223; MecA_N; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:AIJ33798.1};
KW   Cell division {ECO:0000313|EMBL:AIJ33798.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028780};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..603
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001715809"
FT   DOMAIN          28..135
FT                   /note="NTF2-like N-terminal transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF05223"
FT   DOMAIN          327..587
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   603 AA;  62614 MW;  4DAA7C98179C747A CRC64;
     MQRLLALLTG AVVLTSALAA CTPRPNDAQP AAQAMLDALV SRDTEGLSSL VDDPSSASAS
     INATWDGLQA DSLDAELTGV SQSENLATAT YSMHWQLPRE RDLSYEAQMT LTQTGDDWTV
     RWQPSVLHPR LGAHQHLELR SITPKEASVV SSDGVELLRP GIAYRLLVDT NAMGTAPETA
     FRISEALAAG HEADRAVPLR DAAQLTTDLE NAQGTYSVAM VPQGAQRAVE DKLGGLAGVR
     LNEEAAMVNA DPSFAPDIMA RVGALVREDL EGEAGWNVSV VNENGAAYEE LEREDAAPAP
     AVHISLDHRV QRAAEAALEP VAGQQAMIVA IRPSTGGILA VAQTPAADKD GNVATMGQYP
     PGSTFKIITA AAGMEKQGLG TGSIVPCPGT MDIFGRTVTN YAGFSLGNVS LESAFAHSCN
     TTFADISTKL APGELAQIGK QFGLGLDMKI PGLDTITGSI PEGEEPLDRT EAGYGQGLDL
     ASPFGMALVA ATAAHGAMPV PYLIQGEKTE LSEEPGAMPP EAVGQLQQMM AAVTAAGGTA
     NGMSAGGDIR GKTGEAEING GSHSWFAGYR ADDDIAFATL VVLGGGSEAA VAITDRMLHN
     LNP
//